Skip to search formSkip to main contentSkip to account menu

MCM complex

Known as: MCM complex location, mini-chromosome maintenance complex, mini-chromosome maintenance complex location 
A hexameric protein complex required for the initiation and regulation of DNA replication. [GOC:jl, PMID:11282021]
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CMG complexpre-replicative complex location

Narrower (1)

MCM core complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Kaposi's Sarcoma-Associated Herpesvirus Deregulates Host Cellular Replication during Lytic Reactivation by Disrupting the MCM Complex through ORF59
KSHV is the causative agent of various lethal malignancies affecting immunocompromised individuals. Both lytic and latent phases… 
2017
2017
The interaction between ATRIP and MCM complex is essential for ATRIP chromatin loading and its phosphorylation in mantle cell lymphoma cells.
AIM The ATR-interacting protein (ATRIP) is responsible for the recognition of DNA damage-induced structure and regulation of… 
2016
2016
Global Proteome Changes in Liver Tissue 6 Weeks after FOLFOX Treatment of Colorectal Cancer Liver Metastases
(1) Oxaliplatin-based chemotherapy for colorectal cancer liver metastasis is associated with sinusoidal injury of liver… 
2012
2012
Cdt1p, through its interaction with Mcm6p, is required for the formation, nuclear accumulation and chromatin loading of the MCM complex
Regulation of DNA replication initiation is essential for the faithful inheritance of genetic information. Replication initiation… 
2011
2011
Arquitectura molecular de un complejo MCM helicasa-primasa
La replicacion de ADN es un proceso esencial en organismos eucariotas y procariotas. Este proceso es indispensable para la… 
2006
2006
Pre-replication complex organization in the atypical DNA replication cycle of Plasmodium falciparum: characterization of the mini-chromosome maintenance (MCM) complex formation.
2004
2004
A CDC6-like Factor from the Archaea Sulfolobus solfataricus Promotes Binding of the Mini-chromosome Maintenance Complex to DNA*
The archaeal replication apparatus appears to be a simplified version of the eukaryotic one with fewer polypeptides and simpler… 
Highly Cited
2003
Highly Cited
2003
CDK‐ and Cdc45‐dependent priming of the MCM complex on chromatin during S‐phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45
Background: MCM and Cdc45 are required for the initiation and elongation stages of eukaryotic DNA replication. Recent studies… 
Highly Cited
1999
Highly Cited
1999
Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly.
The minichromosome maintenance (MCM) proteins MCM2-MCM7 are conserved eukaryotic replication factors that assemble in a… 
1974
1974
Nefronoftisi familiare: Revisione della letteratura e presentazione di 4 casi della stessa famiglia
SummaryNephronophthisis (N) and medullary cystic disease (MCD) can occur in the same family group. In a single family of 11… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)