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MCM complex

Known as: MCM complex location, mini-chromosome maintenance complex, mini-chromosome maintenance complex location 
A hexameric protein complex required for the initiation and regulation of DNA replication. [GOC:jl, PMID:11282021]
National Institutes of Health

Papers overview

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2019
2019
The DNA translocation activity of the minichromosome maintenance (MCM) complex powers DNA strand separation of the replication… Expand
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Highly Cited
2017
Highly Cited
2017
The minichromosome maintenance complex (MCM) hexameric complex (Mcm2–7) forms the core of the eukaryotic replicative helicase… Expand
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Highly Cited
2015
Highly Cited
2015
DNA replication in eukaryotes is strictly regulated by several mechanisms. A central step in this replication is the assembly of… Expand
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Highly Cited
2014
Highly Cited
2014
Initiation of eukaryotic DNA replication requires phosphorylation of the MCM complex by Dbf4-dependent kinase (DDK), composed of… Expand
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Highly Cited
2012
Highly Cited
2012
CCAAT/enhancer-binding protein (C/EBP) β is required for both mitotic clonal expansion (MCE) and terminal adipocyte… Expand
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Review
2005
Review
2005
  • M. Lei
  • Current cancer drug targets
  • 2005
  • Corpus ID: 1324633
The MCM complex controls the once per cell cycle DNA replication in eukaryotic cells. In a process known as DNA replication… Expand
Highly Cited
2005
Highly Cited
2005
The homomultimeric archaeal mini-chromosome maintenance (MCM) complex serves as a simple model for the analogous heterohexameric… Expand
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Highly Cited
2003
Highly Cited
2003
Background: MCM and Cdc45 are required for the initiation and elongation stages of eukaryotic DNA replication. Recent studies… Expand
Review
2002
Review
2002
To maintain genome integrity in eukaryotes, DNA must be duplicated precisely once before cell division occurs. A process called… Expand
Review
2001
Review
2001
  • M. Lei, B. Tye
  • Journal of cell science
  • 2001
  • Corpus ID: 14331263
The exact duplication of a genome once per cell division is required of every proliferating cell. To achieve this goal… Expand
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