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MCM complex

Known as: MCM complex location, mini-chromosome maintenance complex, mini-chromosome maintenance complex location 
A hexameric protein complex required for the initiation and regulation of DNA replication. [GOC:jl, PMID:11282021]
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CMG complexpre-replicative complex location

Narrower (1)

MCM core complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Open-ringed structure of the Cdt1–Mcm2–7 complex as a precursor of the MCM double hexamer
The minichromosome maintenance complex (MCM) hexameric complex (Mcm2–7) forms the core of the eukaryotic replicative helicase… 
2017
2017
MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway.
The roles and mechanisms of mini-chromosome maintenance complex component 7 (MCM7) amplification and overexpression in esophageal… 
2016
2016
Host cell interactome of PA protein of H5N1 influenza A virus in chicken cells.
2016
2016
Comprehensive Characterization of Minichromosome Maintenance Complex (MCM) Protein Interactions Using Affinity and Proximity Purifications Coupled to Mass Spectrometry.
The extensive identification of protein-protein interactions under different conditions is an important challenge to understand… 
Highly Cited
2012
Highly Cited
2012
Histone demethylase Kdm4b functions as a co-factor of C/EBPβ to promote mitotic clonal expansion during differentiation of 3T3-L1 preadipocytes
CCAAT/enhancer-binding protein (C/EBP) β is required for both mitotic clonal expansion (MCE) and terminal adipocyte… 
2011
2011
Molecular support for the recognition of the Mycoblastus fucatus group as the new genus Violella (Tephromelataceae, Lecanorales)
Abstract The crustose lichen genus Mycoblastus in the Northern Hemisphere includes eight recognized species sharing large, simple… 
2010
2010
The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells
The stepwise assembly of pre-replicative complexes (pre-RCs) is essential for the initiation of DNA replication. Cdt1, a… 
Highly Cited
2003
Highly Cited
2003
CDK‐ and Cdc45‐dependent priming of the MCM complex on chromatin during S‐phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45
Background: MCM and Cdc45 are required for the initiation and elongation stages of eukaryotic DNA replication. Recent studies… 
Review
2002
Review
2002
Control of DNA replication licensing in a cell cycle
To maintain genome integrity in eukaryotes, DNA must be duplicated precisely once before cell division occurs. A process called… 
Highly Cited
1999
Highly Cited
1999
Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly.
The minichromosome maintenance (MCM) proteins MCM2-MCM7 are conserved eukaryotic replication factors that assemble in a… 
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