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Pre-Replication Complex

Known as: pre-replication complex location, pre-replicative complex, pre-replicative complex location 
The Origin Recognition Complex (ORC) in eukaryotic cells selects genomic sites where pre-replication complexes (pre-RCs) can be assembled. Subsequent… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Meier-Gorlin syndrome (ear, patella and short-stature syndrome) is an autosomal recessive primordial dwarfism syndrome… Expand
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Highly Cited
2009
Highly Cited
2009
During pre-replication complex (pre-RC) formation, origin recognition complex (ORC), Cdc6, and Cdt1 cooperatively load the 6… Expand
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Highly Cited
2007
Highly Cited
2007
The c-Myc proto-oncogene encodes a transcription factor that is essential for cell growth and proliferation and is broadly… Expand
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Review
2007
Review
2007
Eukaryotic DNA replication is regulated to ensure all chromosomes replicate once and only once per cell cycle. Replication begins… Expand
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Highly Cited
2007
Highly Cited
2007
DNA replication of eukaryotic chromosomes initiates at a number of discrete loci, called replication origins. Distribution and… Expand
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Highly Cited
2004
Highly Cited
2004
Cohesin is a multi-subunit, ring-shaped protein complex that holds sister chromatids together from the time of their synthesis in… Expand
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Highly Cited
2003
Highly Cited
2003
Eukaryotic chromosomal DNA replication requires a two-step assembly of replication proteins on origins; formation of the… Expand
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Review
2002
Review
2002
Eukaryotic DNA replication is an intricate process that requires the coordinate and tightly regulated action of numerous… Expand
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Highly Cited
1997
Highly Cited
1997
In S. cerevisiae, the chromatin structure of DNA replication origins changes as cells become competent for DNA replication… Expand
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Highly Cited
1997
Highly Cited
1997
Faithful inheritance of genetic information requires that DNA be copied only once each cell cycle. Initiation of DNA replication… Expand
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