pifithrin

 
National Institutes of Health

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2015
2015
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment. It is the most frequent cause of… (More)
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Highly Cited
2004
Highly Cited
2004
No neuroprotective compounds are clinically available for the treatment of ischemic stroke. The potential salutary effect of… (More)
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Highly Cited
2004
Highly Cited
2004
Pifithrin-alpha (PFTalpha) was originally thought to be a specific inhibitor of signaling by the tumor suppressor protein p53… (More)
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Highly Cited
2004
Highly Cited
2004
Doxorubicin (DOX), a widely used chemotherapeutic agent, exhibits cardiotoxicity as an adverse side effect in cancer patients… (More)
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2004
2004
The present experiments were designed to evaluate the effects of pifithrin-alpha (PFT-alpha), which is a p53 inhibitor, on… (More)
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2004
2004
Liu, Xuwan, Chu C. Chua, Jinping Gao, Zhongyi Chen, Cathy L. C. Landy, Ronald Hamdy, and Balvin H. L. Chua. Pifithrinprotects… (More)
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Highly Cited
2003
Highly Cited
2003
We established previously that X-linked inhibitor of apoptosis protein (Xiap) is a determinant of cisplatin (CDDP) resistance in… (More)
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Highly Cited
2003
Highly Cited
2003
Ischemic injury to the kidney is characterized in part by nucleotide depletion and tubular cell death in the form of necrosis or… (More)
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Highly Cited
2002
Highly Cited
2002
Pax-3 is a transcription factor that is expressed in the neural tube, neural crest, and dermomyotome. We previously showed that… (More)
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Highly Cited
1999
Highly Cited
1999
Chemotherapy and radiation therapy for cancer often have severe side effects that limit their efficacy. Because these effects are… (More)
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