pifithrin-alpha

Known as: 2-(2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone, PFT alpha, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)- benzothiazolyl)ethanone hydrobromide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2015
01220062015

Papers overview

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2015
2015
ThehumanpregnaneX receptor (hPXR) is a xenobiotic-sensing nuclear receptor that transcriptionally regulates drug metabolism… (More)
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2013
2013
TRAIL and agonistic death receptor-specific antibodies can induce apoptosis in cancer cells with little cytotoxicity to normal… (More)
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2012
2012
A study was undertaken in order to understand the kinetics and mechanism of the chemical oxidation of N,N-diethyl-m-toluamide, an… (More)
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2011
2011
AIMS Pifithrin α (PFTα), an inhibitor of the p53 protein, is regarded as a lead compound for cancer and neurodegenerative disease… (More)
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2010
2010
We have previously shown that whereas T-cells from normal individuals undergo accumulation of p53 and apoptosis when treated with… (More)
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2010
2010
INTRODUCTION The nuclear factor-kappaB (NF-NF-κ) has been shown to upregulate pro-apoptotic mediators such as TRAIL-DR4/-DR5… (More)
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2006
2006
There has been intense investigation regarding the interaction between the phosphatase and tensin homologue deleted on chromosome… (More)
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