phthalazinol
National Institutes of Health
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Phthalazinol (1) was converted to phthalazinol nitrate (2) and phthalazinol dinitrate (3) by treatment with fuming nitric acid…
Side effects of a drug sometimes lead to new uses. Phthalazinol is an inhibitor of cyclic adenosine monophosphate (cAMP…
EG-626, 7-ethoxycarbonyl-6, 8-dimethyl-4-hydroxymethyl-1 (2H)-phthalazinone, was found to be a considerably potent cardiotonic…
Experiments in monkeys have demonstrated that the chronic vasospasm and arterial injury reaction produced by subarachnoid blood…
Using an in vitro system designed to measure arterial constriction, we have demonstrated the importance of platelet function in…
The inhibitor constants of several inhibitors for cyclic AMP- and cyclic GMP-phosphodiesterase from various organs are compared…
Phthalazinol given to rabbits intravenously in doses of 0.1-1.0mg/kg prevented significantly the myocardial infarction induced by…
Arterial endothelial cells, which are capable of phagocytizing carbon particles of the same size as beta- and pre-beta…