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peptidase activity

Known as: peptide hydrolase activity, hydrolase, acting on peptide bonds, proteinase activity 
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino… 
National Institutes of Health

Related topics

Related topics

8 relations
EndopeptidasesPeptide HydrolasesProteolytic Enzymepeptidase activator activity

Broader (1)

Proteolysis

Narrower (1)

endopeptidase activity

Papers overview

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Highly Cited
1999
Highly Cited
1999
Hyperphosphorylation of the Hepatitis C Virus NS5A Protein Requires an Active NS3 Protease, NS4A, NS4B, and NS5A Encoded on the Same Polyprotein
ABSTRACT The nonstructural protein NS5A of hepatitis c virus (HCV) has been demonstrated to be a phosphoprotein with an apparent… 
Highly Cited
1996
Highly Cited
1996
DNA-dependent Protein Kinase Is a Target for a CPP32-like Apoptotic Protease*
We demonstrate that the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) is specifically, proteolytically cleaved… 
Highly Cited
1995
Highly Cited
1995
Proteinase expression in early mouse embryos is regulated by leukaemia inhibitory factor and epidermal growth factor.
Several proteinases from different multigene families have been implicated in the uterine invasion required for establishment of… 
Highly Cited
1992
Highly Cited
1992
Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting.
The inability to detect insulin-like growth factor binding protein-3 (IGFBP-3) in some circumstances by Western ligand blot… 
Highly Cited
1990
Highly Cited
1990
Osteoblasts display receptors for and responses to leukemia‐inhibitory factor
Specific binding of leukemia‐inhibitory factor (LIF) to osteoblasts, but not multinucleated osteoclasts, was demonstrated by… 
Highly Cited
1989
Highly Cited
1989
Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors.
Highly Cited
1982
Highly Cited
1982
Susceptibility of the Myelin‐Associated Glycoprotein and Basic Protein to a Neutral Protease in Highly Purified Myelin from Human and Rat Brain
Abstract: Incubation of highly purified human myelin at 25° and pH 8 in ammonium bicarbonate buffer resulted in the conversion of… 
Highly Cited
1977
Highly Cited
1977
Enkephalin catabolism in vitro and in vivo
Highly Cited
1976
Highly Cited
1976
A calcium-activated neutral protease in normal and dystrophic human muscle.
  • N. KarC. Pearson
  • Clinica chimica acta; international journal of…
  • 1976
  • Corpus ID: 32711561
Highly Cited
1973
Highly Cited
1973
Carboxypeptidase from yeast. Large scale preparation and the application to COOH-terminal analysis of peptides and proteins.
Abstract In order to render the carboxypeptidase from yeast more readily available for use in sequence studies in protein… 
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