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peptidase activity

Known as: peptide hydrolase activity, hydrolase, acting on peptide bonds, proteinase activity 
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Coagulation and the immune system interact in several physiological and pathological conditions, including tissue repair, host… Expand
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Review
2017
Review
2017
Proteases play a pivotal role in regulating important physiological processes from food digestion to blood clotting. They are… Expand
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Highly Cited
2003
Highly Cited
2003
γ-Secretase is a membrane protein complex with an unusual aspartyl protease activity that catalyses the regulated intramembranous… Expand
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Review
2000
Review
2000
  • M. Cunningham
  • Clinical microbiology reviews
  • 2000
  • Corpus ID: 22526471
Group A streptococci are model extracellular gram-positive pathogens responsible for pharyngitis, impetigo, rheumatic fever, and… Expand
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Highly Cited
1998
Highly Cited
1998
Caspases are intracellular proteases that function as initiators and effectors of apoptosis. The kinase Akt and p21-Ras, an Akt… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome are severe microvascular disorders of platelet… Expand
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Highly Cited
1997
Highly Cited
1997
Nitric oxide (NO) has emerged as an important endogenous inhibitor of apoptosis, and here we report that NO prevents hepatocyte… Expand
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Highly Cited
1996
Highly Cited
1996
Expression of BAX, without another death stimulus, proved sufficient to induce a common pathway of apoptosis. This included the… Expand
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Highly Cited
1995
Highly Cited
1995
Lactacystin is a Streptomyces metabolite that inhibits cell cycle progression and induces neurite outgrowth in a murine… Expand
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Highly Cited
1992
Highly Cited
1992
CLOSTRIDIAL neurotoxins, including tetanus toxin and the seven serotypes of botulinum toxin (A–G), are produced as single chains… Expand
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