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p14ARF Protein

Known as: Cdkn2a(p14ARF), Tumor Suppressor Protein p14ARF, Tumor Suppressor Protein p14ARF [Chemical/Ingredient] 
A gene product of the p16 tumor suppressor gene (GENES, P16). It antagonizes the function of MDM2 PROTEIN (which regulates P53 TUMOR SUPPRESSOR… 
National Institutes of Health

Related topics

Related topics

13 relations
CDKN2A geneCDKN2A wt AlleleCyclin-Dependent Kinase Inhibitor p16In Blood

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p19(ARF) protein, mouse

Papers overview

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2015
2015
Prostate cancer: On the right path—Stat3 signalling controls the ARF–Mdm2–p53 tumour-suppressor pathway
Prostate cancer: On the right path—Stat3 signalling controls the ARF–Mdm2–p53 tumour-suppressor pathway 
2013
2013
Correction: Mimicking p14ARF Phosphorylation Influences Its Ability to Restrain Cell Proliferation
The image reported in Figure 3A, IP anti X-press, in the lower right hand panel (corresponding to the immunoprecipitated T8D… 
2012
2012
ErbB 380 kDa , a nuclear variant of the ErbB 3 receptor , binds to the Cyclin D 1 promoter to activate cell proliferation but is negatively controlled by p 14 ARF
2009
2009
Deregulation of the tumour suppressor genes p 14 ARF , p 15 INK 4 b , p 16 INK 4 a and p 53 in basal cell carcinoma
Background Basal cell carcinoma (BCC) is a locally aggressive slowly growing tumour that rarely metastasizes and is mostly seen… 
2008
2008
MBD 2-Mediated Transcriptional Repression of the p 14 ARF Tumor Suppressor Gene in Human Colon Cancer Cells
Objective: The p14 ARF and p16 INK4A tumor suppressor genes are commonly inactivated by aberrant methylation of their promoter… 
2007
2007
MDM 2 Splice Variants Predominantly Localize to the Nucleoplasm Mediated by a COOH-Terminal Nuclear Localization Signal
Of the >40 alternative and aberrant splice variants of MDM2 that have been described to date, the majority has lost both the well… 
Review
2005
Review
2005
E2F and p53 make a nice couple: converging pathways in apoptosis
It has been known for some time that p53 activation elicits growth arrest in normal cells, whereas activation of this tumor… 
2004
2004
Identification of the E 1 A-Regulated Transcription Factor p 120 E 4 F as an Interacting Partner of the RASSF 1 A Candidate Tumor Suppressor Gene
Epigenetic inactivation of the candidate tumor suppressor gene RASSF1A is a frequent and critical event in the pathogenesis of… 
2003
2003
Molecular analysis of tumor suppressor genes, Rb, p53, p16INK4A, p15INK4B and p14ARF in natural killer cell neoplasms
2002
2002
Hypermethylation of the p 14 ARF Gene in Ulcerative Colitis-associated Colorectal Carcinogenesis 1
The p14 protein directly inhibits the MDM-2 oncoprotein, which mediates degradation of the p53 protein. It has been shown that…