p14ARF Protein

Known as: Cdkn2a(p14ARF), Tumor Suppressor Protein p14ARF, Tumor Suppressor Protein p14ARF [Chemical/Ingredient] 
A gene product of the p16 tumor suppressor gene (GENES, P16). It antagonizes the function of MDM2 PROTEIN (which regulates P53 TUMOR SUPPRESSOR… (More)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Glioblastoma (GB) is the most common and aggressive primary brain malignancy, with poor prognosis and a lack of effective… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE There are no good genomic markers of survival in patients with advanced colorectal cancer. The CpG island methylator… (More)
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Highly Cited
2004
Highly Cited
2004
To clarify the roles of Bmi-1 in colorectal carcinoma, we examined the expression of Bmi-1 in 41 samples out of 46 colorectal… (More)
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Highly Cited
2004
Highly Cited
2004
Human tumors are believed to harbor a disabled p53 tumor suppressor pathway, either through direct mutation of the p53 gene or… (More)
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Highly Cited
2002
Highly Cited
2002
The t(8;21) is one of the most frequent chromosomal translocations associated with acute leukemia. This translocation creates a… (More)
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Highly Cited
2001
Highly Cited
2001
The INK4a-ARF locus encodes two tumor suppressor proteins involved in cell-cycle regulation, p16INK4a and p14ARF, whose functions… (More)
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Highly Cited
2001
Highly Cited
2001
The alternative product of the human INK4a/ARF locus, p14ARF, has the potential to act as a tumour suppressor by binding to and… (More)
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Highly Cited
2000
Highly Cited
2000
The adenovirus mutant dl1520 (ONYX-015) does not express the E1B-55K protein that binds and inactivates p53. This virus… (More)
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Highly Cited
1999
Highly Cited
1999
In this study we established the simultaneous status of TP53, p16, p14ARF and PTEN tumor suppressor genes in 34 randomly chosen… (More)
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Highly Cited
1998
Highly Cited
1998
The two distinct proteins encoded by the CDKN2A locus are specified by translating the common second exon in alternative reading… (More)
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