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oxazepam glucuronide

Known as: beta-D-Glucopyranosiduronic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl 
National Institutes of Health

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AdumbranSeraxTazepamanalogs & derivatives

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Oxazepam

Papers overview

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2013
2013
Direct determination of diazepam and its glucuronide metabolites in human whole blood by μElution solid-phase extraction and liquid chromatography-tandem mass spectrometry.
2012
2012
Extending the detection window of diazepam by directly analyzing its glucuronide metabolites in human urine using liquid chromatography-tandem mass spectrometry.
2010
2010
A novel reductive transformation of oxazepam to nordiazepam observed during enzymatic hydrolysis.
beta-Glucuronidase is an enzyme often employed to de-conjugate beta-glucuronides during urinary drug testing for benzodiazepines… 
2008
2008
The concentration of oxazepam and oxazepam glucuronide in oral fluid, blood and serum after controlled administration of 15 and 30 mg oxazepam.
AIMS To measure and compare the concentration-time profiles of oxazepam and oxazepam glucuronide in blood, serum and oral fluid… 
1995
1995
(S)oxazepam glucuronidation is inhibited by ketoprofen and other substrates of UGT2B7.
1,4-Benzodiazepine anxiolytics such as diazepam and halazepam are converted in vivo to oxazepam, an active metabolite with a… 
1993
1993
Metabolism and elimination of oxazepam in B6C3F1 and Swiss-Webster mice.
The National Toxicology Program has recently determined oxazepam to be hepatocarcinogenic in mice. To aid in the assessment of… 
1990
1990
Oxidative versus conjugative biotransformation of temazepam.
Twenty-four healthy volunteers, aged 21-59 years, received single 30 mg oral doses of the benzodiazepine hypnotic temazepam… 
1985
1985
The influence of diflunisal on the pharmacokinetics of oxazepam.
Single dose pharmacokinetics of oxazepam, 30 mg, have been studied in six healthy male volunteers in the absence of diflunisal… 
Highly Cited
1984
Highly Cited
1984
Effect of brussels sprouts and cabbage on drug conjugation
Ten healthy subjects were fed three diets for 10 days each: a control diet, a cabbage and brussels sprouts–containing diet, and… 
1965
1965
Metabolism of diazepam in dogs: transformation to oxazepam.
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