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Oxazepam

Known as: (RS)-Oxazepam, (+-)-Oxazepam, 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl- 
A synthetic benzodiazepine derivative with anxiolytic and sedative hypnotic properties. Although the mechanism of action has not been fully… Expand
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (9)

AdumbranOvaribranSeraxSeresta
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Alcohol Withdrawal DeliriumAngle Closure GlaucomaAnxiety DisordersBenzodiazepines
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Broader (7)

Anti-Anxiety AgentsAnticonvulsantsBenzodiazepineBenzodiazepinones
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Anti-anxiety drugs and fish behavior: Establishing the link between internal concentrations of oxazepam and behavioral effects.
Psychoactive drugs are frequently detected in the aquatic environment. The evolutionary conservation of the molecular targets of… Expand
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Highly Cited
2013
Highly Cited
2013
Dilute Concentrations of a Psychiatric Drug Alter Behavior of Fish from Natural Populations
Unintended Recipients of Antidepressants Pharmaceuticals are used to treat a wide variety of ailments and conditions in humans… Expand
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Highly Cited
2005
Highly Cited
2005
Environmental fate of pharmaceuticals in water/sediment systems.
In recent years there has been growing interest on the occurrence and the fate of pharmaceuticals in the aquatic environment… Expand
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Highly Cited
2004
Highly Cited
2004
A simple and reliable conflict procedure for testing anti-anxiety agents
The effects of three benzodiazepines (chlordiazepoxide, diazepam, and oxazepam), meprobamate, pentobarbital, d-amphetamine… Expand
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Highly Cited
2004
Highly Cited
2004
UDP-Glucuronosyltransferase (UGT) 2B15 Pharmacogenetics: UGT2B15 D85Y Genotype and Gender Are Major Determinants of Oxazepam Glucuronidation by Human Liver
Oxazepam is a commonly used 1,4-benzodiazepine anxiolytic drug that is polymorphically metabolized in humans. However, the… Expand
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Highly Cited
2002
Highly Cited
2002
Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.
(R,S)-Oxazepam is a 1,4-benzodiazepine anxiolytic drug that is metabolized primarily by hepatic glucuronidation. In previous… Expand
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Highly Cited
2001
Highly Cited
2001
Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam.
OBJECTIVE Passionflower (Passiflora incarnata) is a folk remedy for anxiety. A double-blind randomized trial compared the… Expand
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Highly Cited
1998
Highly Cited
1998
The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).
UGT2B7 has been cloned and expressed previously in COS cells and HK293 cells. Two forms have been identified: one with a tyrosine… Expand
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Review
1981
Review
1981
Clinical Pharmacokinetics of Oxazepam and Lorazepam
SummaryOxazepam and lorazepam are 3-hydroxy benzodiazepine derivatives used as sedatives and anxiolytics. The major metabolic… Expand
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Highly Cited
1980
Highly Cited
1980
Oxazepam kinetics: effects of age and sex.
Thirty-eight healthy male and female volunteers, 22 to 84 years of age, ingested single 30-mg doses of oxazepam tablets in the… Expand
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