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Oxazepam

Known as: (RS)-Oxazepam, (+-)-Oxazepam, 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl- 
A synthetic benzodiazepine derivative with anxiolytic and sedative hypnotic properties. Although the mechanism of action has not been fully… Expand
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (9)

AdumbranOvaribranSeraxSeresta
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Alcohol Withdrawal DeliriumAngle Closure GlaucomaAnxiety DisordersBenzodiazepines
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Broader (7)

Anti-Anxiety AgentsAnticonvulsantsBenzodiazepineBenzodiazepinones
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents.
In the year 2010, effluents from 90 European wastewater treatment plants (WWTPs) were analyzed for 156 polar organic chemical… Expand
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Highly Cited
2013
Highly Cited
2013
Dilute Concentrations of a Psychiatric Drug Alter Behavior of Fish from Natural Populations
Unintended Recipients of Antidepressants Pharmaceuticals are used to treat a wide variety of ailments and conditions in humans… Expand
Highly Cited
2005
Highly Cited
2005
Environmental fate of pharmaceuticals in water/sediment systems.
In recent years there has been growing interest on the occurrence and the fate of pharmaceuticals in the aquatic environment… Expand
Highly Cited
2002
Highly Cited
2002
Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.
(R,S)-Oxazepam is a 1,4-benzodiazepine anxiolytic drug that is metabolized primarily by hepatic glucuronidation. In previous… Expand
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Highly Cited
2001
Highly Cited
2001
Passionflower in the treatment of generalized anxiety: a pilot double‐blind randomized controlled trial with oxazepam
Objective: Passionflower (Passiflora incarnata) is a folk remedy for anxiety. A double‐blind randomized trial compared the… Expand
Review
1991
Review
1991
Paroxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness.
Paroxetine is a potent and selective inhibitor of the neuronal reuptake of serotonin, thereby facilitating serotoninergic… Expand
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Review
1990
Review
1990
Zolpidem. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential.
Zolpidem is an imidazopyridine, a chemically novel nonbenzodiazepine hypnotic agent which acts at the benzodiazepine omega 1… Expand
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Review
1981
Review
1981
Clinical Pharmacokinetics of Oxazepam and Lorazepam
SummaryOxazepam and lorazepam are 3-hydroxy benzodiazepine derivatives used as sedatives and anxiolytics. The major metabolic… Expand
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Highly Cited
1980
Highly Cited
1980
Oxazepam kinetics: effects of age and sex.
Thirty-eight healthy male and female volunteers, 22 to 84 years of age, ingested single 30-mg doses of oxazepam tablets in the… Expand
Highly Cited
1976
Highly Cited
1976
Normal disposition of oxazepam in acute viral hepatitis and cirrhosis.
Oxazepam (Serax) is a tranquilizer-sedative of the benzodiazepine group that is predominantly metabolized to a pharmacologically… Expand
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