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Oxazepam
Known as:
(RS)-Oxazepam
, (+-)-Oxazepam
, 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-
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A synthetic benzodiazepine derivative with anxiolytic and sedative hypnotic properties. Although the mechanism of action has not been fully…
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National Institutes of Health
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Related topics
Related topics
39 relations
Narrower (9)
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Alcohol Withdrawal Delirium
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Anxiety Disorders
Benzodiazepines
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Broader (7)
Anti-Anxiety Agents
Anticonvulsants
Benzodiazepine
Benzodiazepinones
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1988
1988
Determination of diazepam and oxazepam using high-performance liquid chromatography and fourth-derivative spectrophotometric techniques.
M. Abdel‐Hamid
,
M. Abuirjeie
In Analysis
1988
Corpus ID: 33809479
Accurate and very precise HPLC and fourth-derivative ultraviolet spectrophotometric methods for the determination of diazepam and…
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1984
1984
Oxazepam pharmacokinetics in thyroid disease.
A. Scott
,
A. Khir
,
P. D. Bewsher
,
G. Hawksworth
British Journal of Clinical Pharmacology
1984
Corpus ID: 19428313
The pharmacokinetics of oxazepam, a drug mainly eliminated by a single step glucuronidation reaction, were studied in seven…
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1980
1980
Influence of cimetidine on the pharmacokinetics of desmethyldiazepam and oxazepam
U. Klotz
,
I. Reimann
European Journal of Clinical Pharmacology
1980
Corpus ID: 12759931
SummaryThe pharmacokinetics of single oral doses of desmethyldiazepam 20 mg or oxazepam 50 mg were studied in 5 healthy…
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1979
1979
Oxazepam esters. 1. Correlation between hydrolysis rates and brain appearance of oxazepam.
G. Maksay
,
Z. Tegyey
,
V. Kemény
,
I. Lukovits
,
L. Otvös
,
É. Pálosi
Journal of Medicinal Chemistry
1979
Corpus ID: 22410331
Esters of the centrally acting oxazepam were investigated to find quantitative correlations between the pharmacokinetics of the…
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1978
1978
Hypnotic activity of 3-hydroxy, N-desmethyldiazepam (oxazepam).
A. Nicholson
,
B. Stone
British Journal of Clinical Pharmacology
1978
Corpus ID: 27826366
Diazepam (5-10 mg) and its hydroxylated metabolites, temazepam (10-20 mg) and oxazepam (15-30 mg), have limited effects on…
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1978
1978
Kinetic investigations of liver microsomal esterases with oxazepam esters.
G. Maksay
,
Z. Tegyey
,
L. Otvös
Hoppe-Seyler´s Zeitschrift für physiologische…
1978
Corpus ID: 35829692
Hepatic microsomal esterases of the mouse responsible for the bioactivation of inactive (prodrug) esters of the centrally acting…
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1977
1977
Oxazepam disposition in uremic patients.
I. Odar-Cederlöf
,
J. Vessman
,
G. Alvan
,
F. Sjöqvist
Acta Pharmacologica et Toxicologica
1977
Corpus ID: 25605536
The pharmacokinetics of oxazepam was investigated in 13 uremic patients. The apparent terminal half-life of oxazepam in plasma…
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1975
1975
Practolol and the nephrotic syndrome.
M. Farr
,
J. Wingate
,
J. Shaw
British medical journal
1975
Corpus ID: 41212743
1974
1974
In vitro hydrolysis of oxazepam succinate half-ester by a stereospecific soluble esterase from different animal species.
M. Salmona
,
C. Saronio
,
R. Bianchi
,
F. Marcucci
,
E. Mussini
Journal of Pharmacy and Science
1974
Corpus ID: 29965478
Abstract The presence of a stereospecific soluble esterase that hydrolyzes the three forms of oxazepam succinate half-ester…
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Highly Cited
1964
Highly Cited
1964
ABSORPTION, METABOLISM, AND EXCRETION OF OXAZEPAM AND ITS SUCCINATE HALF-ESTER.
S. Walkenstein
,
R. Wiser
,
C. Gudmundsen
,
H. Kimmel
,
R. Corradino
Journal of Pharmacy and Science
1964
Corpus ID: 26330594
C 14 -Oxazepam was administered orally to dogs, rats, and pigs. Radioassay of blood, various tissues, and excreta indicated that…
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