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Benzodiazepinones
Known as:
Benzodiazepinones [Chemical/Ingredient]
National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (45)
3-hydroxy-2-oxoquazepam
AHN 086
Adumbran
BI-RJ 70
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Broader (1)
Benzodiazepines
In Blood
agonists
antagonists & inhibitors
chemical synthesis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones.
Hasan Mtiraoui
,
Kévin Renault
,
M. Sanselme
,
M. Msaddek
,
P. Renard
,
C. Sabot
Organic & biomolecular chemistry
2017
Corpus ID: 46803734
A novel and practical synthesis of 3-benzoylquinoxalin-2(1H)-ones from benzodiazepin-2-ones in two steps from commercially…
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2013
2013
Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
R. Kester
,
Andrew F Donnell
,
+29 authors
Barry S Goggin
Journal of medicinal chemistry
2013
Corpus ID: 21010463
The IAPs are key regulators of the apoptotic pathways and are commonly overexpressed in many cancer cells. IAPs contain one to…
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2012
2012
Iridium catalyzed asymmetric hydrogenation of cyclic imines of benzodiazepinones and benzodiazepines.
K. Gao
,
Bo Wu
,
Chang-Bin Yu
,
Qing‐An Chen
,
Zhi-Shi Ye
,
Yong‐Gui Zhou
Organic letters
2012
Corpus ID: 44466578
Highly enantioselective Ir-catalyzed hydrogenation of seven-membered cyclic imines of benzodiazepinones and benzodiazepines was…
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Highly Cited
2011
Highly Cited
2011
1,3-Dipolar cycloaddition-decarboxylation reactions of an azomethine ylide with isatoic anhydrides: formation of novel benzodiazepinones.
Asha M. D'souza
,
Nadia Spiccia
,
+6 authors
J. H. Ryan
Organic letters
2011
Corpus ID: 207751266
A nonstabilized azomethine ylide reacts with a wide range of substituted isatoic anhydrides to afford novel 1,3-benzodiazepin-5…
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Highly Cited
2009
Highly Cited
2009
Chemical Biology Investigation of Cell Death Pathways Activated by Endoplasmic Reticulum Stress Reveals Cytoprotective Modulators of ASK1*
Inki Kim
,
Chih-Wen Shu
,
+5 authors
John Calvin Reed
Journal of Biological Chemistry
2009
Corpus ID: 205376751
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) is caused by many disease-relevant conditions, inducing…
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2009
2009
Combinatorial Library Synthesis and Biological Evaluation of Pyrazolo[4,3‐e][1,4]diazepine as a Potential Privileged Structure
Ju-Yeon Lee
,
Yong‐Chul Kim
ChemMedChem
2009
Corpus ID: 205644899
A privileged structure: A library of tetrahydro‐1,4‐pyrazolo‐diazepin‐8(2H)‐ones was designed and synthesized to probe the…
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2007
2007
Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): a gamma-secretase inhibitor with Abeta…
C. Prasad
,
M. Zheng
,
+15 authors
D. Barten
Bioorganic & medicinal chemistry letters
2007
Corpus ID: 46353242
Highly Cited
2007
Highly Cited
2007
Polymeric sulfated amino acid surfactants: a class of versatile chiral selectors for micellar electrokinetic chromatography (MEKC) and MEKC-MS.
S. A. Rizvi
,
Jie Zheng
,
R. Apkarian
,
S. Dublin
,
S. Shamsi
Analytical chemistry
2007
Corpus ID: 25329443
In this work, three amino acid-derived (l-leucinol, l-isoleucinol, l-valinol) sulfated chiral surfactants are synthesized and…
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1993
1993
Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases.
G. Massolini
,
A. Aubry
,
A. McGann
,
I. Wainer
Biochemical pharmacology
1993
Corpus ID: 9597053
Review
1988
Review
1988
The story of flumazenil.
W. Haefely
,
W. Hunkeler
European journal of anaesthesiology. Supplement
1988
Corpus ID: 19443859
The story of flumazenil is a typical example of a serendipitous preclinical drug discovery. Our search for specific…
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