FAQ

Benzodiazepinones

Known as: Benzodiazepinones [Chemical/Ingredient] 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
012319882017

Related topics

Related topics

50 relations

Narrower (46)

3-hydroxy-N-desalkyl-2-oxoquazepam4'-chlorodiazepamAnthramycinBMS-871
(More)
administration & dosageantagonists & inhibitorsaspects of radiation effectschemical synthesis

Related mentions per year

Related mentions per year

1951-2018
1960198020002020
Benzodiazepinones
chemical synthesis
Lorazepam
Flunitrazepam
Oxazepam
camazepam

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Regioselective Halogenation of 1,4-Benzodiazepinones via CH Activation
This article reports an efficient CH activation process for regioselective halogenation of 1,4-benzodiazepinones. Direct… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2013
2013
Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
The IAPs are key regulators of the apoptotic pathways and are commonly overexpressed in many cancer cells. IAPs contain one to… (More)
Is this relevant?
2012
2012
Iridium catalyzed asymmetric hydrogenation of cyclic imines of benzodiazepinones and benzodiazepines.
Highly enantioselective Ir-catalyzed hydrogenation of seven-membered cyclic imines of benzodiazepinones and benzodiazepines was… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
2012
2012
Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation.
A two-step strategy for the synthesis of arrays of tricyclic tetrazolo-fused benzodiazepines and benzodiazepinones has been… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) is caused by many disease-relevant conditions, inducing… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2007
2007
Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): a gamma-secretase inhibitor with Abeta…
We report on the design of benzodiazepinones as peptidomimetics at the carboxy terminus of hydroxyamides. Structure-activity… (More)
Is this relevant?
2003
2003
Solid-phase synthesis of 7-acylamino-1,4-benzodiazepine-2,5-diones.
A method for the synthesis of polymer-bound 7-acylamino-benzodiazepine-2,5-diones is described. The amino group of an alpha-amino… (More)
Is this relevant?
2002
2002
Soluble polymer-supported synthesis of benzodiazepinones.
Soluble polymer-supported synthetic method provides a highly efficient route for the construction of biologically important 1,5… (More)
Is this relevant?
1998
1998
A non-peptide compound which can mimic the effect of thrombopoietin via c-Mpl.
Thrombopoietin (TPO) is a cytokine which plays a central role in megakaryopoiesis and platelet production by binding to its cell… (More)
Is this relevant?
1998
1998
Synthesis of 7,8-(methylenedioxy)-1-phenyl-3,5-dihydro-4H-2, 3-benzodiazepin-4-ones as novel and potent noncompetitive AMPA receptor antagonists.
A group of 7,8-(methylenedioxy)-1-phenyl-3,5-dihydro-4H-2, 3-benzodiazepin-4-ones was synthesized and assayed for antagonism of… (More)
Is this relevant?