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Benzodiazepinones

Known as: Benzodiazepinones [Chemical/Ingredient] 
National Institutes of Health

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3-hydroxy-2-oxoquazepamAHN 086AdumbranBI-RJ 70

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Benzodiazepines
In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

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2019
2019
Chemoselectivity for Alkene Cleavage by Palladium-Catalyzed Intramolecular Diazo Group Transfer from Azide to Alkene.
Alkenes can be cleaved by means of the (3+2) cycloaddition and subsequent cycloreversion of 1,3-dipoles, classically ozone (O3… 
2017
2017
Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones.
A novel and practical synthesis of 3-benzoylquinoxalin-2(1H)-ones from benzodiazepin-2-ones in two steps from commercially… 
2017
2017
Correction: Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones.
Correction for 'Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones' by Hasan Mtiraoui, et al… 
2015
2015
γ-Turn Mimicry with Benzodiazepinones and Pyrrolobenzodiazepinones Synthesized from a Common Amino Ketone Intermediate.
To investigate diazepinone analogues as γ-turn mimics, seven 1,4-benzodiazepin-2-ones 6 and fourteen pyrrolo[1,2-d][1,4… 
2015
2015
Chemoselective Alkylation for Diversity-Oriented Synthesis of 1,3,4-Benzotriazepin-2-ones and Pyrrolo[1,2][1,3,4]benzotriazepin-6-ones, Potential Turn Surrogates.
1,3,4-Benzotriazepin-2-ones garner interest for medicinal applications, in part due to their relationship with benzodiazepinones… 
2011
2011
Benzodiazepinone Derivatives as CRTH2 Antagonists.
Multiple CRTH2 antagonists are currently evaluated in human clinical trials for asthma and chronic obstructive pulmonary disease… 
2009
2009
Combinatorial Library Synthesis and Biological Evaluation of Pyrazolo[4,3‐e][1,4]diazepine as a Potential Privileged Structure
A privileged structure: A library of tetrahydro‐1,4‐pyrazolo‐diazepin‐8(2H)‐ones was designed and synthesized to probe the… 
Highly Cited
2007
Highly Cited
2007
Polymeric sulfated amino acid surfactants: a class of versatile chiral selectors for micellar electrokinetic chromatography (MEKC) and MEKC-MS.
In this work, three amino acid-derived (l-leucinol, l-isoleucinol, l-valinol) sulfated chiral surfactants are synthesized and… 
2004
2004
Evaluation of two pairs of chiral stationary phases: effects from the length of the achiral spacers.
Two pairs of chiral stationary phases (CSPs) with different C(2)-symmetric central parts were prepared and evaluated by… 
1989
1989
[1,4-Disubstituted 1,3-dihydro-2H-1,5-benzo- and chlorobenzodiazepin-2-ones with activity on the central nervous system].
In pursuing the study on pyridodiazepinone derivatives, in order to verify the variation of biological activity induced by… 
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