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osteoclast development

Known as: osteoclast cell development 
The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

osteoclast differentiation

Narrower (1)

osteoclast maturation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The 12/15-lipoxygenase pathway promotes osteoclast development and differentiation
Although 12/15-lipoxygenase (12/15-LO) has been implicated as negative regulator of systemic bone mass in mice and humans, the… 
2005
2005
Limited Rescue of Osteoclast‐Poor Osteopetrosis After Successful Engraftment by Cord Blood From an Unrelated Donor
We report on a case of osteoclast‐poor osteopetrosis who received a hematopoietic stem cell graft and, despite hematological… 
2004
2004
Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).
Osteoclasts regulate homeostasis of bone development. A defect in osteoclast development results in osteopetrosis. Recently, the… 
Highly Cited
2002
Highly Cited
2002
Adenoviral transfer of murine oncostatin M elicits periosteal bone apposition in knee joints of mice, despite synovial inflammation and up-regulated expression of interleukin-6 and receptor activator…
2002
2002
The role of LFA-1 in osteoclast development induced by co-cultures of mouse bone marrow cells and MC3T3-G2/PA6 cells.
Interactions between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) influence the… 
1997
1997
Osteoclast development from hematopoietic stem cells: apparent divergence of the osteoclast lineage prior to macrophage commitment.
To further clarify the progression of osteoclast development, the relationship of clonogenic osteoclast progenitors (CFU-O) to… 
1997
1997
Generation of multinuclear tartrate‐resistant acid phosphatase positive osteoclasts in liquid culture of purified human peripheral blood CD34+ progenitors
Circulating CD34+ cells were isolated from leukapheresis products collected from patients with ovarian cancer. CD34… 
Highly Cited
1993
Highly Cited
1993
Leukemia inhibitory factor inhibits osteoclastic resorption, growth, mineralization, and alkaline phosphatase activity in fetal mouse metacarpal bones in culture
Leukemia inhibitory factor (LIF) has been reported to affect bone metabolism, but results are variable. We examined the effect of… 
Highly Cited
1991
Highly Cited
1991
Gene expression during skeletal development in three osteopetrotic rat mutations. Evidence for osteoblast abnormalities.
1989
1989
Osteoclastic acid ATPase: biochemical and histochemical studies of the osteopetrotic mutations in the rat.
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