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osteoclast maturation

A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state… Expand
National Institutes of Health

Papers overview

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2015
2015
The role of Notch signaling in osteoclast differentiation is controversial with conflicting experimental evidence indicating both… Expand
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Highly Cited
2012
Highly Cited
2012
Osteoclast differentiation is critically dependent on calcium (Ca2+) signaling. Transient receptor potential vanilloid 4 (TRPV4… Expand
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Review
2012
Review
2012
Aims:  To describe the mechanisms of action of denosumab, a novel antiresorptive agent, contrasting it with other antiresorptive… Expand
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Review
2011
Review
2011
The bone is a very common site of metastasis in patients with advanced cancer. Skeletal metastases are most common in breast and… Expand
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Highly Cited
2011
Highly Cited
2011
High maternal blood glucose levels caused by diabetes mellitus can irreversibly lead to maldevelopment of the growing fetus with… Expand
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Highly Cited
2006
Highly Cited
2006
Matrix-producing osteoblasts and bone-resorbing osteoclasts maintain bone homeostasis. Osteoclasts are multinucleated, giant… Expand
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Review
2005
Review
2005
Bone homeostasis is maintained by a balance between bone resorption by osteoclasts and bone formation by osteoblasts. Osteoblasts… Expand
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Highly Cited
2005
Highly Cited
2005
The receptor activator of NF-κB (RANK) belongs to the neuregulin/tumor necrosis factor (TNF) receptor superfamily and is… Expand
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Highly Cited
2001
Highly Cited
2001
Bone cancer pain most commonly occurs when tumors originating in breast, prostate, or lung metastasize to long bones, spinal… Expand
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1999
1999
The increase of bone resorption and reduction of bone mass in postmenopausal women can be prevented by treatment with estrogen… Expand
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