osteoclast maturation

A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state… (More)
National Institutes of Health

Papers overview

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2015
2015
The role of Notch signaling in osteoclast differentiation is controversial with conflicting experimental evidence indicating both… (More)
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2009
2009
Regulation of the formation and function of bone-resorbing osteoclasts (OCs) is a key to understanding the pathogenesis of… (More)
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2008
2008
Hsp90 inhibitors are being evaluated extensively in patients with advanced cancers. However, the impact of Hsp90 inhibition on… (More)
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2008
2008
Intracellular signals involved in the maturation and function of osteoclasts are poorly understood. Here, we demonstrate that… (More)
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Highly Cited
2007
Highly Cited
2007
Cathepsin K and MMP-9 are considered to be the most abundant proteases in osteoclasts. TRAP is a marker for osteoclasts, and… (More)
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Highly Cited
2006
Highly Cited
2006
Matrix-producing osteoblasts and bone-resorbing osteoclasts maintain bone homeostasis. Osteoclasts are multinucleated, giant… (More)
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2004
2004
OBJECTIVE Rheumatoid arthritis (RA) is characterized by progressive joint destruction. The aim of this study was to clarify the… (More)
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2004
2004
Although 14-day-old mouse embryonic calvarial cells cultured in plastic culture dishes in the presence of 1α,25-dihydroxyvitamin… (More)
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Highly Cited
2001
Highly Cited
2001
Bone cancer pain most commonly occurs when tumors originating in breast, prostate, or lung metastasize to long bones, spinal… (More)
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Review
1998
Review
1998
Two physiological regulators of osteoclast maturation have recently been identified: the secreted protein osteoprotegerin and the… (More)
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