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Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1
TLDR
Selective inhibition of c-Fos/AP-1 resolves arthritis in a preclinical model of the disease.
Mammalian Clock Gene Cryptochrome Regulates Arthritis via Proinflammatory Cytokine TNF-α
TLDR
The biological clock and arthritis influence each other, and this interplay can influence human health and disease.
Interferon-alpha in lupus psychosis.
TLDR
The hypothesis that IFN alpha, possibly synthesized in the brain, is the cause of the manifestation of psychosis in patients with SLE is supported.
Identification of the gene loci that predispose to rheumatoid arthritis.
TLDR
Three principal chromosome regions of linkage, D1S253/214, D8S556 and DXS1232, have been identified which the authors call RA1, RA2 and RA3 for RA disease loci.
Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells.
TLDR
The CpG island in the DR3 gene promoter was specifically methylated to down-modulate the expression of DR-3 protein in rheumatoid synovial cells, which may provide resistance to apoptosis in RA synovIAL cells.
Role of the MICA polymorphism in systemic lupus erythematosus.
TLDR
The MICA polymorphism is genetically associated with SLE, and MICA appears to contribute to the pathogenesis of SLE by modulating NK cell function.
Transradial Approach for Transcatheter Arterial Chemoembolization in Patients With Hepatocellular Carcinoma: Comparison with Conventional Transfemoral Approach
TLDR
TACE by the new transradial approach was found to have therapeutic efficacy with lower complications comparable to that of the conventional transfemoral approach and time required for catheterizaiton and complications.
A preliminary study on the interferon-alpha treatment for xerostomia of Sjögren's syndrome.
TLDR
The result suggests a beneficial effect of this agent in increasing the saliva production of patients with primary Sjögren's syndrome.
Unruptured pseudoaneurysm of the cystic artery with acute calculous cholecystitis incidentally detected by computed tomography
TLDR
The first case of an unruptured pseudoaneurysm of the cystic artery with concurrent acute calculous cholecystitis in a 71-year-old man is reported, highlighting the usefulness of CT for both diagnosis and patient management.
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