osteoclast differentiation

Known as: osteoclast cell differentiation 
The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
010020019772017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Inactivation of beta-catenin in mesenchymal progenitors prevents osteoblast differentiation; inactivation of Lrp5, a gene… (More)
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Highly Cited
2002
Highly Cited
2002
Signaling by RANKL is essential for terminal differentiation of monocytes/macrophages into osteoclasts. The TRAF6 and c-Fos… (More)
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Highly Cited
2000
Highly Cited
2000
Osteoclast differentiation factor (ODF, also called RANKL/TRANCE/OPGL) stimulates the differentiation of osteoclast progenitors… (More)
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Highly Cited
2000
Highly Cited
2000
Osteoprotegerin-ligand (OPGL) is a key osteoclast differentiation/activation factor essential for bone remodeling. We report that… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE Osteoclast differentiation factor (ODF; also known as osteoprotegerin ligand, receptor activator of nuclear factor… (More)
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Highly Cited
1999
Highly Cited
1999
A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via… (More)
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Highly Cited
1999
Highly Cited
1999
The physiological role of the TNF receptor (TNFR) family member, RANK, was investigated by generating RANK-deficient mice. RANK… (More)
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Highly Cited
1998
Highly Cited
1998
The ligand for osteoprotegerin has been identified, and it is a TNF-related cytokine that replaces the requirement for stromal… (More)
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Highly Cited
1998
Highly Cited
1998
Osteoclasts, the multinucleated cells that resorb bone, develop from hematopoietic cells of monocyte/macrophage lineage… (More)
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Highly Cited
1997
Highly Cited
1997
A novel secreted glycoprotein that regulates bone resorption has been identified. The protein, termed Osteoprotegerin (OPG), is a… (More)
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