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olanzapine

Known as: olanzapine [Chemical/Ingredient], 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, Zolafren 
A synthetic derivative of thienobenzodiazepine with antipsychotic, antinausea, and antiemetic activities. As a selective monoaminergic antagonist… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The first-line treatment for psychotic disorders remains antipsychotic drugs with receptor antagonist properties at D2-like… Expand
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Review
2017
Review
2017
Antipsychotic-induced weight gain is a major management problem for clinicians. It has been shown that weight gain and obesity… Expand
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Review
2017
Review
2017
IntroductionThere is strong evidence from randomized controlled trials (RCTs) that second-generation antipsychotic (SGA… Expand
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Review
2017
Review
2017
OBJECTIVE Antipsychotic drug efficacy may have decreased over recent decades. The authors present a meta-analysis of all placebo… Expand
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Review
2016
Review
2016
randomised trials comparing two treatments directly (socalled direct evidence). The major criticism has been that meta-analysis… Expand
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Review
2016
Review
2016
IMPORTANCE Antipsychotics are used increasingly in youth for nonpsychotic and off-label indications, but cardiometabolic adverse… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of… Expand
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE Dopamine D2 receptor occupancy measurements provide a valid predictor of antipsychotic response, extrapyramidal side… Expand
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Highly Cited
1996
Highly Cited
1996
The affinities of olanzapine, clozapine, haloperidol, and four potential antipsychotics were compared on binding to the neuronal… Expand
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