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olanzapine

Known as: olanzapine [Chemical/Ingredient], 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, Zolafren 
A synthetic derivative of thienobenzodiazepine with antipsychotic, antinausea, and antiemetic activities. As a selective monoaminergic antagonist… 
National Institutes of Health

Related topics

Related topics

30 relations
Adrenergic alpha-Antagonists [MoA]Bipolar DisorderDrug AllergyFluoxetine 25 MG / olanzapine 6 MG Oral Capsule [Symbyax]

Broader (4)

AntiemeticsAntipsychotic AgentsBenzodiazepinesSerotonin Uptake Inhibitors

Narrower (6)

LY 170053SymbyaxZydisZyprexa

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Does switching to a new antipsychotic improve outcomes? Data from the CATIE Trial
Highly Cited
2008
Highly Cited
2008
Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics.
Review
2008
Review
2008
Review of smoking cessation treatments for people with mental illness
This article reviews the current literature regarding treatments for smoking cessation in both the general population and in… 
Highly Cited
2006
Highly Cited
2006
Differential profile of antipsychotics at serotonin 5-HT1A and dopamine D2S receptors coupled to extracellular signal-regulated kinase.
Highly Cited
2005
Highly Cited
2005
The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia
Highly Cited
2005
Highly Cited
2005
Australian and New Zealand Clinical Practice Guidelines for the Treatment of Anorexia Nervosa
  • J. Haliburn
  • Australian and New Zealand journal of psychiatry…
  • 2005
  • Corpus ID: 10166221
Anorexia nervosa (AN) is a serious and potentially fatal mental illness. Its key feature is deliberate loss of weight through… 
Highly Cited
2000
Highly Cited
2000
N-Methyl-D-aspartate (NMDA) receptor-based treatment approaches in schizophrenia: the first decade.
The study of excitatory amino acids (EAA) [e.g. glutamate (Glu), aspartate] as neurotransmitters has resulted in many new and… 
Review
1999
Review
1999
Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia
Available evidence indicates that clozapine is the most effective antipsychotic currently used for the pharmacotherapy of… 
Review
1997
Review
1997
Efficacy of olanzapine: an overview of pivotal clinical trials.
Olanzapine is a new "atypical" antipsychotic agent that belongs chemically to the thienobenzodiazepine class. Its relatively… 
Highly Cited
1995
Highly Cited
1995
Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine
Prepulse inhibition (PPI) of the startle reflex provides an operational measure of sensorimotor gating. Deficits in PPI are… 
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