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olanzapine

Known as: olanzapine [Chemical/Ingredient], 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, Zolafren 
A synthetic derivative of thienobenzodiazepine with antipsychotic, antinausea, and antiemetic activities. As a selective monoaminergic antagonist… 
National Institutes of Health

Related topics

Related topics

30 relations
Adrenergic alpha-Antagonists [MoA]Bipolar DisorderDrug AllergyFluoxetine 25 MG / olanzapine 6 MG Oral Capsule [Symbyax]

Broader (4)

AntiemeticsAntipsychotic AgentsBenzodiazepinesSerotonin Uptake Inhibitors

Narrower (6)

LY 170053SymbyaxZydisZyprexa

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis
Highly Cited
2009
Highly Cited
2009
Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis
Highly Cited
2006
Highly Cited
2006
Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis.
OBJECTIVE This study assessed the efficacy of olanzapine in delaying or preventing conversion to psychosis and reducing symptoms… 
Highly Cited
2005
Highly Cited
2005
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.
BACKGROUND The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents… 
Highly Cited
2004
Highly Cited
2004
Olanzapine vs haloperidol: treating delirium in a critical care setting
ObjectiveTo compare the safety and estimate the response profile of olanzapine, a second-generation antipsychotic, to haloperidol… 
Highly Cited
2003
Highly Cited
2003
Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of… 
Review
1999
Review
1999
The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia.
Cognitive function is markedly impaired in most patients with schizophrenia. Antecedents of this impairment are evident in… 
Highly Cited
1999
Highly Cited
1999
Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia.
OBJECTIVE Dopamine D2 receptor occupancy measurements provide a valid predictor of antipsychotic response, extrapyramidal side… 
Review
1999
Review
1999
Olanzapine. Pharmacokinetic and pharmacodynamic profile.
Multicentre trials in patients with schizophrenia confirm that olanzapine is a novel antipsychotic agent with broad efficacy… 
Highly Cited
1996
Highly Cited
1996
Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine
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