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This study assessed the efficacy of olanzapine in delaying or preventing conversion to psychosis and reducing symptoms… Expand BACKGROUND
The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents… Expand Cognitive impairment is a core feature of schizophrenia and a major impediment to social and vocational rehabilitation. A number… Expand BACKGROUND
Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of… Expand ObjectiveTo compare the safety and estimate the response profile of olanzapine, a second-generation antipsychotic, to haloperidol… Expand OBJECTIVE
Newer antipsychotic drugs have shown promise in ameliorating neurocognitive deficits in patients with schizophrenia… Expand Cognitive function is markedly impaired in most patients with schizophrenia. Antecedents of this impairment are evident in… Expand OBJECTIVE
Dopamine D2 receptor occupancy measurements provide a valid predictor of antipsychotic response, extrapyramidal side… Expand Multicentre trials in patients with schizophrenia confirm that olanzapine is a novel antipsychotic agent with broad efficacy… Expand The affinities of olanzapine, clozapine, haloperidol, and four potential antipsychotics were compared on binding to the neuronal… Expand