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olanzapine

Known as: olanzapine [Chemical/Ingredient], 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, Zolafren 
A synthetic derivative of thienobenzodiazepine with antipsychotic, antinausea, and antiemetic activities. As a selective monoaminergic antagonist… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
OBJECTIVE This study assessed the efficacy of olanzapine in delaying or preventing conversion to psychosis and reducing symptoms… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents… Expand
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Review
2005
Review
2005
Cognitive impairment is a core feature of schizophrenia and a major impediment to social and vocational rehabilitation. A number… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of… Expand
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Highly Cited
2003
Highly Cited
2003
ObjectiveTo compare the safety and estimate the response profile of olanzapine, a second-generation antipsychotic, to haloperidol… Expand
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE Newer antipsychotic drugs have shown promise in ameliorating neurocognitive deficits in patients with schizophrenia… Expand
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Review
1999
Review
1999
Cognitive function is markedly impaired in most patients with schizophrenia. Antecedents of this impairment are evident in… Expand
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE Dopamine D2 receptor occupancy measurements provide a valid predictor of antipsychotic response, extrapyramidal side… Expand
Review
1999
Review
1999
Multicentre trials in patients with schizophrenia confirm that olanzapine is a novel antipsychotic agent with broad efficacy… Expand
Highly Cited
1996
Highly Cited
1996
The affinities of olanzapine, clozapine, haloperidol, and four potential antipsychotics were compared on binding to the neuronal… Expand