olanzapine

Known as: olanzapine [Chemical/Ingredient], 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, Zolafren 
A synthetic derivative of thienobenzodiazepine with antipsychotic, antinausea, and antiemetic activities. As a selective monoaminergic antagonist… (More)

Topic mentions per year

Topic mentions per year

1986-2018
020040019862018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
OBJECTIVE When a schizophrenia patient has an inadequate response to treatment with an antipsychotic drug, it is unclear what… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
OBJECTIVE Deficits in working memory and in prefrontal cortical physiology are important outcome measures in schizophrenia, and… (More)
  • table 1
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
OBJECTIVE Few long-term studies have compared the efficacy and safety of typical and atypical antipsychotic medications directly… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
To compare the safety and estimate the response profile of olanzapine, a second-generation antipsychotic, to haloperidol in the… (More)
  • figure 1
  • table 1
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
OBJECTIVE Newer antipsychotic drugs have shown promise in ameliorating neurocognitive deficits in patients with schizophrenia… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
OBJECTIVE Dopamine D2 receptor occupancy measurements provide a valid predictor of antipsychotic response, extrapyramidal side… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
OBJECTIVE The primary intent of this study was to compare the efficacy and safety of olanzapine and placebo in the treatment of… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The affinities of olanzapine, clozapine, haloperidol, and four potential antipsychotics were compared on binding to the neuronal… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Olanzapine is a potential new "atypical" antipsychotic agent. The double-blind acute phase of this study compared three dosage… (More)
Is this relevant?