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normethadone

Known as: Desmethylmethadone, nor-methadone, 6-dimethylamino-4,4-diphenyl-3-hexanone 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Analgesics, OpioidAntitussive AgentsMethadone
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Phenyl‐substituted Normethadones: Synthesis and Pharmacology
Phenyl‐substituted normethadone derivatives were synthesized and their affinity (IC50) for opioid receptors was determined by… 
1993
1993
Non-opioid antitussives and methadone differentially influence hippocampal long-term potentiation in freely moving rats.
1983
1983
Methadone radioimmunoassay: two simple methods
Two simple and economical radioimmunoassays for methadone in blood or urine are described. Haemolysis, decomposition, common… 
1978
1978
Evidence for the importance of N-dealkylation in opioid pharmacology☆
1974
1974
Reflexogenic prolongation of respiratory pauses: A potential mode of action of antitussives
Four clinically effective antitussives and 37059 (1-Ethylaminoethyl-5-methoxy-benzocyclobutene), a substance with singular… 
1973
1973
[Conformation of normethadone].
1971
1971
Identification and quantitative determination of some metabolites of methadone, isomethadone and normethadone
Isomethadone and normethadone are metabolized by microsomal preparations of guinea‐pig liver to yield 2‐ethyl‐1,4‐dimethyl‐3,3… 
1971
1971
The influence of methyl substitution on the N‐demethylation and N‐oxidation of normethadone in animal species
N‐Monodemethylation and N‐oxidation were shown to be the major routes of metabolism of normethadone, (—)‐methadone and… 
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