norcocaine

 

Topic mentions per year

Topic mentions per year

1974-2016
05101519742016

Papers overview

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2000
2000
The first step in the oxidative metabolism of cocaine is N-demethylation to norcocaine, which is further N-hydroxylated to more… (More)
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1999
1999
We have compared the pharmacokinetics of bolus dose cocaine administration with that of its three most important metabolites… (More)
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1993
1993
Cocaine was metabolized to norcocaine by microsomes prepared from lymphoblastoid cells expressing transfected human P-450 3A4… (More)
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1993
1993
Cocaine is known to be associated with hepatotoxicity in laboratory animals, and there is recent evidence that it also induces… (More)
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1984
1984
In the mid1970's, norcocaine was identified as a metabolite of cocaine in rat brain tissue. We extend these studies by… (More)
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1983
1983
The mixed function oxidase system of mouse liver microsomes converts norcocaine to N-hydroxynorcocaine (NHNC). This metabolite… (More)
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1982
1982
Norcocaine nitroxide was found to be produced via the one-electron oxidation of N-hydroxynorcocaine by hepatic microsomal enzymes… (More)
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1980
1980
The potency of cocaine, relative to d-amphetamine, to initiate and maintain intravenous self-administration behavior by dogs (n=5… (More)
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1979
1979
The hydrolysis of cocaine and its N-demethylated product, norcocaine, by esterases was examined in liver and serum. Both liver… (More)
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1979
1979
1. The metabolism of [3H]norcocaine, N-hydroxy[3H]norcocaine and cocaine-N-oxide has been investigated in rats after i.v… (More)
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