myristoylation
National Institutes of Health
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To determine the role of the myristoylated amino terminus of Galpha in G protein activation, nine individual cysteine mutations…
It has been proposed that N-terminal myristoylation of calcineurin B is necessary for the membrane association of calcineurin. We…
DNA damage is recognized as a central component of carcinogenesis. DNA-damaging agents activate a number of signal transduction…
Calcineurin is a serine/threonine protein phosphatase composed of a catalytic subunit, calcineurin A (58 kDa), and a NH2-terminal…
The myristoylated alanine-rich protein kinase C substrate (MARCKS) is a widely expressed, prominent substrate for protein kinase…
Heterotrimeric G protein alpha-subunits localized on the cytoplasmic face of Golgi membranes are involved in regulating vesicle…
N-myristoyltransferase (NMT) is an essential eukaryotic enzyme that catalyzes the transfer of myristate to the NH2-terminal…
GTPase-inhibiting mutations of the alpha subunit (alpha i2) of the G protein, Gi2, result in constitutive activation of alpha i2…