M. Vaughan

Publications407
h-index68
Citations16,115
Highly Influential Citations333
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • J. Moss
  • 880 Publications • 34,230 Citations
  • S. Tsai
  • 89 Publications • 2,513 Citations
  • R. Adamik
  • 65 Publications • 1,982 Citations
  • R. Kahn
  • 263 Publications • 15,999 Citations
  • Publications
  • Influence
beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.
TLDR
An essential role for ARF proteins in regulating beta2-adrenergic receptor endocytosis is suggested through regulation of ARF protein activation by GRK-mediated recruitment of the GIT1 ARF GAP to the plasma membrane.
View on PubMed
Molecules in the ARF Orbit*
TLDR
Criteria for designation as an ARF have been the ability to activate cholera toxin and to rescue mutant Saccharomyces cerevisiae bearing the lethal double deletion of ARF1 and ARF2 genes.
View on Publisher
GIT Proteins, A Novel Family of Phosphatidylinositol 3,4,5-Trisphosphate-stimulated GTPase-activating Proteins for ARF6*
TLDR
The results suggest that although the mechanism of GTP hydrolysis is probably very similar in these two families of ARF GAPs, GIT proteins might specifically regulate the activity of ARf6 in cells in coordination with phosphatidylinositol 3-kinase signaling pathways.
View on Publisher
HORMONE-SENSITIVE LIPASE AND MONOGLYCERIDE LIPASE ACTIVITIES IN ADIPOSE TISSUE.
View on PubMed
Structure and Function of ARF Proteins: Activators of Cholera Toxin and Critical Components of Intracellular Vesicular Transport Processes (*)
View on Publisher
Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.
View on PubMed
Characterization of an ADP-ribosylation Factor-like 1 Protein inSaccharomyces cerevisiae *
TLDR
Biochemical analyses of purified recombinant yeast ARL1 (yARL1) protein revealed properties similar to those ARF and ARL2 proteins, including the ability to bind and hydrolyze GTP, and it may offer an opportunity to define an ARL function in another kind of vesicular trafficking, such as the regulated secretory pathway.
View on Publisher
Purification and Cloning of a Brefeldin A-inhibited Guanine Nucleotide-exchange Protein for ADP-ribosylation Factors*
TLDR
Two new clones for the ∼200-kDa BIG1 and BIG2 should facilitate characterization of this rather different family of proteins as well as the elucidation of mechanisms of regulation of BFA-sensitive ARF function in Golgi transport.
View on Publisher
Activation of rat brain phospholipase D by ADP-ribosylation factors 1,5, and 6: separation of ADP-ribosylation factor-dependent and oleate-dependent enzymes.
TLDR
The effects of recombinant ARF proteins from the three classes on cholera toxin activity did not correlate with those on PLD, consistent with the notion that different aspects of ARF structure are involved in the two functions.
View on PubMed
Adp-Ribosylating Toxins and G Proteins: Insights into Signal Transduction
Bacterial ADP-ribosyltransferases: toxins and related proteins Guanine nucleotide-binding proteins coupled to signal transduction in animal cells ADP ribosylation in bacteria and animal cells
...
...