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- Publications
- Influence
Cytotoxic arylnaphthalene lignans from a Vietnamese acanthaceae, Justicia patentiflora.
- S. Susplugas, N. Hung, +4 authors F. Guéritte
- Biology, Medicine
- Journal of natural products
- 5 May 2005
One new norlignan (1) and five new lignans (2-6) were isolated from the leaves and stems of Justicia patentiflora by a bioassay-guided purification. Five known compounds, carinatone, diphyllin,… Expand
Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages.
- K. Abbas, J. Breton, +6 authors J. Drapier
- Biology, Medicine
- Free radical biology & medicine
- 1 July 2011
Peroxiredoxins (Prx's) are a family of peroxidases that maintain thiol homeostasis by catalyzing the reduction of organic hydroperoxides, H₂O₂, and peroxynitrite. Under conditions of oxidative… Expand
Antibacterial Labdane Diterpenoids from Vitex vestita.
- Nina Corlay, M. Lecsö-Bornet, +7 authors M. Litaudon
- Chemistry, Medicine
- Journal of natural products
- 2 June 2015
A large-scale in vitro screening of tropical plants using an antibacterial assay permitted the selection of several species with significant antibacterial activities. Bioassay-guided purification of… Expand
Reduction-responsive cholesterol-based block copolymer vesicles for drug delivery.
We developed a new robust reduction-responsive polymersome based on the amphiphilic block copolymer PEG-SS-PAChol. The stability and robustness were achieved by the smectic physical cross-linking of… Expand
Overexpression of the angiogenic tetrapeptide AcSDKP in human malignant tumors.
- J. Liu, Michal Kusinski, +6 authors J. Wdzieczak-Bakala
- Medicine
- Anticancer research
- 1 September 2008
BACKGROUND
The natural tetrapeptide acetyl-Ser-Asp-Lys-Pro (AcSDKP), generated from thymosin beta4 following its cleavage by prolyl oligopeptidase (POP), is a physiological stimulator of… Expand
Evidence for an association of high levels of endogenous Acetyl-Ser-Asp-Lys-Pro, a potent mediator of angiogenesis, with acute myeloid leukemia development
- J. Liu, J. Bignon, +4 authors J. Wdzieczak-Bakala
- Biology, Medicine
- Leukemia & lymphoma
- 1 January 2006
Evidence from clinical and laboratory studies suggests that angiogenesis is important in the progression of solid tumours and hematologic malignancies. We have shown that the naturally occurring… Expand
Cytotoxic 3,4-seco-Atisane Diterpenoids from Croton barorum and Croton goudotii.
- Olga L Rakotonandrasana, F. Raharinjato, +4 authors P. Rasoanaivo
- Medicine, Biology
- Journal of natural products
- 17 September 2010
In a screening program directed to the discovery of new anticancer agents from Madagascan plants, ethyl acetate extracts of Croton barorum and C. goudotii showed strong cytotoxic activity, with 100%… Expand
HLA class II alleles in isocyanate-induced asthma.
- J. Bignon, Y. Aron, +7 authors D. Charron
- Biology, Medicine
- American journal of respiratory and critical care…
- 1994
Studying genetic factors that control human immune responsiveness may further our understanding of specific types of asthma in which the role of immune factors is uncertain to date. HLA Class II gene… Expand
Epidemiologic investigation of respiratory effects related to environmental exposure to asbestos inside insulated buildings.
- S. Cordier, P. Lázár, P. Brochard, J. Bignon, J. Ameille, J. P. Proteau
- Medicine
- Archives of environmental health
- 1 September 1987
The respiratory effects of environmental pollution by asbestos inside university buildings were studied by comparing radiographic, clinical, and functional parameters among three groups of workers… Expand
Epidemiological evidence on the carcinogenicity of silica: factors in scientific judgement.
- C. Soutar, A. Robertson, B. G. Miller, A. Searl, J. Bignon
- Medicine
- The Annals of occupational hygiene
- 2000
In view of the extended debate and differing opinions on whether crystalline silica is a human carcinogen, we have reviewed a selection of epidemiological reports, to identify the areas of… Expand