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Restricting the availability of iron is an important strategy for defense against bacterial infection1,2,3. Mycobacterium… Expand Iron is a prerequisite for in vitro growth of mycobacteria.Iron is an obligate cofactor for at least 40 different enzymes encoded… Expand To multiply and cause disease in the host, Mycobacterium tuberculosis must acquire iron from the extracellular environment at… Expand Mycobacterium tuberculosis, the primary agent of tuberculosis, must acquire iron from the host to cause infection. To do so, it… Expand Methods were devised to purify the cell-associated, iron-binding compounds known as mycobactins from the closely related species… Expand Thirty-nine strains of rapidly growing mycobacteria were examined for the production of mycobactins (lipid-soluble, iron-binding… Expand Nine different strains of mycobacteria grown on media deficient in iron all produced mycobactins. Most strains produced one… Expand Mycobactin S has been isolated from Mycobacterium smegmatis and from Mycobacterium sp. Olitzky & Gershon, strain 2, and… Expand A single pure component was isolated from mycobactin P by countercurrent distribution; its side chain is n-cis-octadec-2-enoyl… Expand