mycobactin

 
National Institutes of Health

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mycobactins

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2013
2013
Disruption of mycobactin biosynthesis leads to attenuation of Mycobacterium tuberculosis for growth and virulence.
BACKGROUND  Low iron availability in the host upregulates the mbt gene cluster of Mycobacterium tuberculosis, which is… (More)
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2012
2012
Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis.
To measure molecular changes underlying pathogen adaptation, we generated a searchable dataset of more than 12,000 mass… (More)
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Highly Cited
2009
Highly Cited
2009
Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition.
The Esx secretion pathway is conserved across Gram-positive bacteria. Esx-1, the best-characterized system, is required for… (More)
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2008
2008
Pyrazoline-based mycobactin analogues as MAO-inhibitors.
3,5-Diaryl carbothioamide pyrazolines designed as mycobactin analogs (mycobacterial siderophore) were reported to be potent… (More)
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2005
2005
Mycobactin-mediated iron acquisition within macrophages.
Restricting the availability of iron is an important strategy for defense against bacterial infection. Mycobacterium tuberculosis… (More)
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Highly Cited
2000
Highly Cited
2000
The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages.
Mycobacterium tuberculosis is an important pathogen of mammals that relies on 2-hydroxyphenyloxazoline-containing siderophore… (More)
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1995
1995
Lack of mycobactin dependence of mycobacteria isolated on Middlebrook 7H11 from clinical cases of ovine paratuberculosis.
Mycobacterium avium subsp. paratuberculosis is distinguished from other mycobacterial species by its dependence on the iron… (More)
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Highly Cited
1990
Highly Cited
1990
Numerical taxonomy of mycobactin-dependent mycobacteria, emended description of Mycobacterium avium, and description of Mycobacterium avium subsp. avium subsp. nov., Mycobacterium avium subsp…
We performed a numerical taxonomy analysis of 38 Mycobacterium paratuberculosis and related mycobacterial strains, including wood… (More)
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1983
1983
Iron-binding compounds of Mycobacterium avium, M. intracellulare, M. scrofulaceum, and mycobactin-dependent M. paratuberculosis and M. avium.
Fifty-three strains of M. avium and related species all produced one or more exochelins, the extracellular iron-binding compounds… (More)
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1975
1975
Extracellular iron acquisition by mycobacteria: role of the exochelins and evidence against the participation of mycobactin.
Mycobacterium bovis var. BCG was grown under iron-deficient conditions in the presence and absence of 1% Tween 80. Mycobactin… (More)
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