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Low iron availability in the host upregulates the mbt gene cluster of Mycobacterium tuberculosis, which is… Expand ABSTRACT The production of mycobactin (MBT) by Mycobacterium tuberculosis is essential for this bacterium to access iron when it… Expand Although the antimalarial agent artemisinin itself is not active against tuberculosis, conjugation to a mycobacterial-specific… Expand The Esx secretion pathway is conserved across Gram-positive bacteria. Esx-1, the best-characterized system, is required for… Expand SUMMARY High-affinity iron acquisition is mediated by siderophore-dependent pathways in the majority of pathogenic and… Expand Restricting the availability of iron is an important strategy for defense against bacterial infection1,2,3. Mycobacterium… Expand The role of iron in the growth and metabolism of M. tuberculosis and other mycobacteria is discussed in relation to the… Expand Mycobacterium tuberculosis is an important pathogen of mammals that relies on 2-hydroxyphenyloxazoline-containing siderophore… Expand BACKGROUND
Many pathogenic bacteria secrete iron-chelating siderophores as virulence factors in the iron-limiting environments of… Expand We performed a numerical taxonomy analysis of 38 Mycobacterium paratuberculosis and related mycobacterial strains, including wood… Expand