monastrol

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
0519992017

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2006
2006
In this paper, we describe a new bioimage informatics system developed for high content screening (HCS) applications with the… (More)
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2006
2006
BACKGROUND A recent crystal structure of monastrol in a ternary complex with the kinesin Eg5 motor domain highlights a novel… (More)
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2005
2005
Monastrol is a small, cell-permeable molecule that arrests cells in mitosis by specifically inhibiting Eg5, a member of the… (More)
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2005
2005
Monastrol is the first characterised small molecule inhibitor of the motor protein Eg5 involved in bipolar mitotic spindle… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND The stable association of chromosomes with both poles of the mitotic spindle (biorientation) depends on spindle… (More)
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Highly Cited
2003
Highly Cited
2003
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle… (More)
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2003
2003
The microtubule-dependent kinesin-like protein Eg5 from Homo sapiens is involved in the assembly of the mitotic spindle. It shows… (More)
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Highly Cited
2002
Highly Cited
2002
Monastrol, a cell-permeable inhibitor of the kinesin Eg5, has been used to probe the dynamic organization of the mitotic spindle… (More)
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Highly Cited
2000
Highly Cited
2000
Monastrol, a cell-permeable small molecule inhibitor of the mitotic kinesin, Eg5, arrests cells in mitosis with monoastral… (More)
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Highly Cited
1999
Highly Cited
1999
Small molecules that perturb specific protein functions are valuable tools for dissecting complex processes in mammalian cells. A… (More)
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