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mitosane

 
National Institutes of Health

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2019
2019
Mitomycins, produced by several Streptomyces strains, are potent anticancer antibiotics that comprise an aziridine ring fused to… Expand
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2003
2003
An enantioselective synthesis of mitosane core (-)-1 has been achieved. Key steps include a rapid assembly of a key eight… Expand
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2001
2001
[reaction: see text]. Synthesis of mitosane 1 in optically pure form is reported. A retrosynthetic plan that proceeds through… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The mitomycins are natural products that contain a variety of functional groups, including aminobenzoquinone- and… Expand
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1994
1994
Pharmacokinetics and metabolism of mitomycin C (MMC) have been studied in NMRI mice bearing MAC 16 colon adenocarcinoma after… Expand
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1987
1987
Mitosenes of both the pyrrolo- and pyrido[1,2-a]indole type have been prepared via a modified Madelung reaction of… Expand
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1986
1986
A NEW PROCEDURE FOR PREPARING analog 7-amino-mitosane of formula wherein: A GROUP ALQ2ES alkylene of straight or branched chain… Expand
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1981
1981
New mitomycin C and porfiromycin analogues were prepared by treating mitomycin A and N-methylmitomycin A with a variety of amines… Expand
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1965
1965
Abstract Trypanosoma equiperdum , a member of the brucei-evansi group of African trypanosomes, is sensitive to the following… Expand
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