mitosane

 

Topic mentions per year

Topic mentions per year

1971-2010
01219712010

Papers overview

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2010
2010
We report that the clinically used antitumor drug mitomycin C is reductively activated in vitro by simple thiols; a mechanism for… (More)
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2003
2003
An enantioselective synthesis of mitosane core (-)-1 has been achieved. Key steps include a rapid assembly of a key eight… (More)
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2001
2001
The UV-Vis and circular dichroism (CD) spectra of several mitomycin antitumor compounds and some of their derivatives were… (More)
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2001
2001
[reaction: see text]. Synthesis of mitosane 1 in optically pure form is reported. A retrosynthetic plan that proceeds through… (More)
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1999
1999
BACKGROUND The mitomycins are natural products that contain a variety of functional groups, including aminobenzoquinone- and… (More)
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1994
1994
Pharmacokinetics and metabolism of mitomycin C (MMC) have been studied in NMRI mice bearing MAC 16 colon adenocarcinoma after… (More)
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1992
1992
BMY-25551, 7-(2-hydroxyethoxy)mitosane, was selected from a series of mitomycin A (MMA) analogues for more detailed study. As… (More)
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1987
1987
Mitosenes of both the pyrrolo- and pyrido[1,2-a]indole type have been prepared via a modified Madelung reaction of… (More)
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1981
1981
New mitomycin C and porfiromycin analogues were prepared by treating mitomycin A and N-methylmitomycin A with a variety of amines… (More)
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