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Mitomycins

Known as: Mitomycin Antineoplastic Antibiotic, Mitomycins [Chemical/Ingredient], mitomycin 
Any of a class of anti-tumor antibiotics acting as alkylating agents. All mitomycins have the backbone of methyl, aziridine, pyrrolo, indole, and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
In order to create a moist environment for rapid wound healing, a hydrogel sheet composed of a blended powder of alginate, chitin… Expand
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Review
1997
Review
1997
This review focuses on the chemical and enzymatic aspects of the reductive activation of mitomycin C, its disulfide analogs KW… Expand
Highly Cited
1997
Highly Cited
1997
OBJECTIVE To establish the long-term, dose-response relationship between the concentration of and duration of exposure to… Expand
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Highly Cited
1994
Highly Cited
1994
BACKGROUND The efficacy of surgery for patients with non-small-cell lung cancer is limited, although recent studies suggest that… Expand
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Highly Cited
1992
Highly Cited
1992
BACKGROUND The use of topical mitomycin (mitomycin-C) as a medical adjunct to pterygium and glaucoma surgery is increasing… Expand
Highly Cited
1992
Highly Cited
1992
Proliferating human Tenon's capsule fibroblasts were exposed for 5 minutes to a wide range of concentrations of fluorouracil… Expand
Review
1990
Review
1990
The mitomycins are antitumor antibiotics that are under investigation now for more than 30 years. Mitomycin C (MMC) is the best… Expand
Highly Cited
1988
Highly Cited
1988
The authors used an antineoplastic-antibiotic agent, mitomycin, in the form of eye drops as adjunctive treatment for primary and… Expand
Review
1986
Review
1986
Vascular complications associated with antineoplastic agents are being reported with increasing frequency. Such vascular toxicity… Expand
Highly Cited
1964
Highly Cited
1964
Mitomycins and porfiromycin, generally nonreactive in the natural oxidized state, behave as bifunctional "alkylating" agents upon… Expand