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Mitomycins

Known as: Mitomycin Antineoplastic Antibiotic, Mitomycins [Chemical/Ingredient], mitomycin 
Any of a class of anti-tumor antibiotics acting as alkylating agents. All mitomycins have the backbone of methyl, aziridine, pyrrolo, indole, and… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (28)

10-decarbamoylmitomycin C10-decarbamoyloxy-9-dehydromitomycin B2,7-diaminomitosene7-(2-hydroxyethoxy)mitosane

Broader (2)

Antibiotics, AntineoplasticAzo Compounds
In BloodMillimole per LiterMitomycinPorfiromycin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Development of a flexible strategy towards FR900482 and the mitomycins.
FR900482 and the mitomycins are two intriguing classes of alkaloid natural products that have analogous biological mechanisms and… 
2011
2011
Aziridines in Natural Product Synthesis
Highly Cited
2004
Highly Cited
2004
Clinical and Histological Healing of Surgical Wounds Treated With Mitomycin C
Objectives/Hypothesis The proven ability of mitomycin C to inhibit fibroblasts in vitro has stimulated its use in research… 
2003
2003
Topical mitomycin C-induced inhibition of postlaminectomy peridural fibrosis in rabbits.
OBJECT The authors conducted a study to determine the effectiveness of mitomycin C in preventing postlaminectomy peridural… 
1998
1998
Ultrastructural changes in rabbit ciliary body after extraocular mitomycin C.
PURPOSE To study the ultrastructural changes in ciliary body epithelium of the rabbit eye after subconjunctival injections of… 
Highly Cited
1994
Highly Cited
1994
Micronucleated erythrocytes as an assay to assess actions by physical and chemical genotoxic agents in Clarias gariepinus.
1991
1991
The effects of topical mitomycin on glaucoma filtration surgery in rabbits.
A prospective, randomized, double-masked, and placebo controlled study was performed to examine the effects of topically applied… 
1985
1985
Beta-carotene as an inhibitor of benzo(a)pyrene and mitomycin C induced chromosomal breaks in the bone marrow of mice.
Female mice of hybrid strain B6C3F1, 8-10 weeks old, were fed on powdered food with or without beta-carotene (100 mg/kg food… 
1983
1983
A rapid screen for cumulative chromosomal damage in mice. Accumulation of circulating micronucleated erythrocytes.
1977
1977
Synthetic studies toward mitomycins. 1. Total synthesis of deiminomitomycin A.
Rossi and J. F. Bunnett, ibid., 38, 3020 (1973); (c) J. V. Hay, T. Hudlicky, and J. F. Wolfe, J. Am. Chem. Soc., 97, 374 (1975… 
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