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Mitomycins

Known as: Mitomycin Antineoplastic Antibiotic, Mitomycins [Chemical/Ingredient], mitomycin 
Any of a class of anti-tumor antibiotics acting as alkylating agents. All mitomycins have the backbone of methyl, aziridine, pyrrolo, indole, and… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (28)

10-decarbamoylmitomycin C10-decarbamoyloxy-9-dehydromitomycin B2,7-diaminomitosene7-(2-hydroxyethoxy)mitosane

Broader (2)

Antibiotics, AntineoplasticAzo Compounds
In BloodMillimole per LiterMitomycinPorfiromycin

Papers overview

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1997
1997
Acute myeloid leukemia following 3M (mitoxantrone, mitomycin and methotrexate) chemotherapy for advanced breast cancer
Acute myeloid leukemia following 3M (mitoxantrone, mitomycin and methotrexate) chemotherapy for advanced breast cancer 
1987
1987
Prevention of cytotoxic drug induced skin ulcers with dimethyl sulfoxide (DMSO) and alpha-tocopherole.
Accidental subcutaneous extravasation of several antineoplastic agents may provoke skin ulcerations for which there has been no… 
1986
1986
A systematic study on the chemical stability of mitomycin A and mitomycin B.
The kinetics and mechanisms of the degradation of mitomycin A and mitomycin B in aqueous solution were investigated by means of… 
1985
1985
Trial of vindesine plus mitomycin in stage-3 non-small cell lung cancer. An active regimen for outpatient treatment.
Ninety patients with stage-3 non-small cell lung cancer were given vindesine (3 mg/sq m) plus mitomycin (10 mg/sq m). Data on… 
1985
1985
Stability of mitomycin admixtures.
The stability of mitomycin in admixtures for continuous intravenous infusion was studied. Mitomycin was reconstituted and diluted… 
1984
1984
Effect of mitomycin C on bone marrow cells in mice.
The total and differential cell counts of femoral bone marrow and peripheral reticulocyte counts were determined in male ddY mice… 
1977
1977
Synthetic studies toward mitomycins. 1. Total synthesis of deiminomitomycin A.
Rossi and J. F. Bunnett, ibid., 38, 3020 (1973); (c) J. V. Hay, T. Hudlicky, and J. F. Wolfe, J. Am. Chem. Soc., 97, 374 (1975… 
1975
1975
Utilization of the intact carbamoyl group of L-(NH2CO-13C,15N) citrulline in mitomycin biosynthesis by Streptomyces verticillatus.
Sir: It was shown previously that both L[guanidino-14C] arginine and L-[ureido-14C] citrulline are efficient mitomycin (I… 
1971
1971
Studies on mitomycins. V. Synthesis of indolequinone and their activities.
Indolequinones postulated as essential structure for activity of mitomycin were synthesized and examined for their antibacterial… 
1967
1967
The effect of mitomycin C on developing chicken embryos.
The mitomycins were isolated from the broth of Streptomyces caespitosus by Hata, Shimada & Ishu (1957). Mitomycin C, one of a…