Porfiromycin

Known as: Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-, Methyl Mitomycin, Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-1,5-dimethyl-,[1aR-(1a.alpha.,8.beta., 8a.alpha.,8b.alpha.)]- (9CI) 
An N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
This randomized phase III study was to evaluate the efficacy and safety of cytoreductive surgery (CRS) plus hyperthermic… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE We compared the outcomes of repeat transurethral resection plus intravesical mitomycin C with initial transurethral… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Peritoneal carcinomatosis of colorectal cancer is probably best treated by cytoreduction and hyperthermic… (More)
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Highly Cited
2004
Highly Cited
2004
HYPOTHESIS The most common cause of palliative resection and recurrence in gastric cancer is peritoneal seeding. This study… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE To evaluate the prognostic value of the posttreatment TNM stage as a predictor of outcome in locally advanced rectal… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE To determine the long-term results of liver transplantation for hepatocellular carcinoma (HCC) measuring 5 cm or larger… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE We assessed the influence of hemoglobin level and r-HuEPO administration on response to chemoradiotherapy, locoregional… (More)
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Review
1999
Review
1999
Although cancer surgery has been of great benefit to patients with large bowel cancer, a flaw that has caused the death of… (More)
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Highly Cited
1985
Highly Cited
1985
Three hundred five patients with advanced pancreatic and gastric carcinoma were randomly assigned to treatment with fluorouracil… (More)
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Highly Cited
1964
Highly Cited
1964
Mitomycins and porfiromycin, generally nonreactive in the natural oxidized state, behave as bifunctional "alkylating" agents upon… (More)
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