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Mitomycin

Known as: Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-, Mitomycine C, MMC 
A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (17)

7-(2-hydroxyethoxy)mitosane7-cysteaminomitosaneAmetycineBL 6783

Broader (1)

Azo Compounds
BOMP protocolBlood Coagulation DisordersHemorrhagic DisordersIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
A study of therapy-related acute leukaemia after mitoxantrone therapy for multiple sclerosis
To evaluate the incidence of therapy-related acute leukaemia (t-AL) after single-agent mitoxantrone (MITO) treatment, we reviewed… 
Highly Cited
2000
Highly Cited
2000
Bactericidal activity of isothiocyanate against pathogens on fresh produce.
The bactericidal activity of allyl and methyl isothiocyanate (AITC and MITC) was tested with a rifampicin-resistant strain of… 
Highly Cited
1998
Highly Cited
1998
Preoperative chemoradiation for extraperitoneal T3 rectal cancer: acute toxicity, tumor response, and sphincter preservation.
Highly Cited
1991
Highly Cited
1991
Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis.
Rodents infected with the nematode parasite Nippostrongylus brasiliensis (Nb) develop intestinal mastocytosis, eosinophilia, and… 
Highly Cited
1982
Highly Cited
1982
Mucosal mast cells. II. Effects of anti-allergic compounds on histamine secretion by isolated intestinal mast cells.
Functional mast cells have been isolated from the lamina propria of the small intestine of rats infected with the nematode… 
Highly Cited
1980
Highly Cited
1980
Preferential activation of mitomycin C to cytotoxic metabolites by hypoxic tumor cells.
Mitomycin C, a bioreductive alkylating agent with clinical utility against several human tumors, was found to be selectively… 
Highly Cited
1978
Highly Cited
1978
Sister chromatid exchange as an indicator of mutagenesis
SISTER chromatid exchange (SCE), that is, the reciprocal interchange of DNA between chromatids, is easily visualised in metaphase… 
Highly Cited
1974
Highly Cited
1974
Induction of sister chromatid exchanges by chemical mutagens and its possible relevance to DNA repair.
Highly Cited
1972
Highly Cited
1972
In vitro and host-mediated "rec-assay" procedures for screening chemical mutagens; and phloxine, a mutagenic red dye detected.
Highly Cited
1970
Highly Cited
1970
Lymphocyte reactivity in vitro: I. Cellular reconstitution of purified lymphocyte response
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