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Immunopathology of intestinal helminth infection
The relationship between intestinal pathology and immune expulsion of gastrointestinal nematodes remains controversial. Parasite expulsion is associated with intestinal pathology in several modelExpand
Immunity to Parasites: How Parasitic Infections are Controlled
Preface to the Second Edition Preface to the First Edition 1. Parasites and parasitism 2. The immune response 3. Experimental immunoparasitology 4. Intracellular Protozoa 5. African trypanosomes 6.Expand
Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction
Abstract  Patients with postinfective irritable bowel syndrome and Trichinella spiralis‐infected mice share many features including visceral hypersensitivity and disordered motility. We assessedExpand
Acquired immunity to Trichuris muris in the albino laboratory mouse.
  • D. Wakelin
  • Biology, Medicine
  • Parasitology
  • 1 August 1967
After infection with the nematode Trichuris muris 70–75% of mice of the Schofield strain developed an immunity to the parasite and eliminated the worms between the 16th and 19th days after infection.Expand
Immunity to parasites
Mucosal T cells regulate Paneth and intermediate cell numbers in the small intestine of T. spiralis‐infected mice
Secretions of Paneth, intermediate and goblet cells have been implicated in innate intestinal host defense. We have investigated the role of T cells in effecting alterations in small intestinalExpand
Role of T helper 2 cells in intestinal goblet cell hyperplasia in mice infected with Trichinella spiralis.
BACKGROUND & AIMS The four principal types of intestinal epithelial cells are derived from multipotent stem cells. Currently, there is no information on factors that regulate commitment of stem cellsExpand
Interactions involving intestinal nematodes of rodents: experimental and field studies
Multiple species infections with parasitic helminths, including nematodes, are common in wild rodent populations. In this paper we first define different types of associations and review experimentalExpand
ELISAs for parasitologists: or lies, damned lies and ELISAs.
The introduction in 1971, by Engvoll and Perlmann, of enzyme labels in immunoassays represented a significant technical advance. Their enzyme-linked immunosorbent assay (ELISA) proved to be asExpand
Nasal Immunization with Homogenate and Peptide Antigens Induces Protective Immunity against Trichinella spiralis
ABSTRACT Mice were successfully immunized against the intestinal nematode Trichinella spiralis by intranasal administration of a 30-mer peptide antigen with cholera toxin B. Immunized mice developedExpand