micafungin

Known as: micafungin [Chemical/Ingredient] 
A semi-synthetic echinocandin derived from a natural product of the fungus Coleophama empedri with potent antifungal activity. Micafungin, like other… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
For Candida species, a bimodal wild-type MIC distribution for echinocandins exists, but resistance to echinocandins is rare. We… (More)
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Highly Cited
2008
Highly Cited
2008
The echinocandins are being used increasingly as therapy for invasive candidiasis. Prospective sentinel surveillance for the… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Invasive candidiasis is increasingly prevalent in premature infants and seriously ill children, and pediatric data on… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Invasive candidosis is increasingly prevalent in seriously ill patients. Our aim was to compare micafungin with… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Invasive candidiasis is an important cause of morbidity and mortality among patients with health care-associated… (More)
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Review
2006
Review
2006
Micafungin, a potent inhibitor of 1,3-beta-D-glucan synthase, has become the second available agent in the echinocandins class… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Micafungin (FK463) is a new lipopeptide compound (echinocandin) with activity against Aspergillus and Candida species… (More)
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Highly Cited
2005
Highly Cited
2005
Candida spp. are the fourth leading cause of bloodstream infections, and non-albicans species are increasing in importance… (More)
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Highly Cited
2005
Highly Cited
2005
Micafungin (FK463) is a new parenteral echinocandin. A multicenter, phase I, open-label, sequential-group dose escalation study… (More)
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Highly Cited
2004
Highly Cited
2004
We hypothesized that chemoprophylaxis with the echinocandin micafungin would be an effective agent for antifungal prophylaxis… (More)
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