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Echinocandins

Known as: Echinocandins [Chemical/Ingredient], echinocandin 
Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be… 
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (16)

ASP9726AculeacinsCaspofunginFKS1 protein, S cerevisiae

Broader (1)

Antifungal Agents
Caspofungin acetateCaspofungin acetate 50 MG InjectionEchinocandin Antifungal [EPC]In Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
New developments and directions in the clinical application of the echinocandins
The echinocandins—caspofungin, anidulafungin and micafungin—are semi-synthetic cyclic hexapeptide antimicrobial agents with… 
2015
2015
Sentinel surveillance of invasive candidiasis in Spain: epidemiology and antifungal susceptibility.
2013
2013
Candida nivariensis as an etiologic agent of vulvovaginal candidiasis in a tertiary care hospital of New Delhi, India.
Review
2006
Review
2006
Efficacy of caspofungin against invasive Candida or invasive Aspergillus infections in neutropenic patients
Neutropenia is an indicator of poor prognosis in patients with fungal infections. All available clinical trial experience from… 
Highly Cited
2006
Highly Cited
2006
Efficacy of amphotericin B or amphotericin B-intralipid in combination with caspofungin against experimental aspergillosis.
Review
2006
Review
2006
Echinocandins in the management of invasive fungal infections, Part 2.
PURPOSE The chemistry, pharmacology, spectrum of activity, resistance, pharmacokinetics, pharmacodynamics, clinical efficacy… 
2006
2006
In vitro interactions of anidulafungin with azole antifungals, amphotericin B and 5-fluorocytosine against Candida species.
Highly Cited
2003
Highly Cited
2003
Forum report: issues in clinical trials of empirical antifungal therapy in treating febrile neutropenic patients.
There is inferential evidence that some patients with prolonged neutropenia and fever not responding to antibacterial agents are… 
Highly Cited
1986
Highly Cited
1986
Total synthesis of echinocandins. I. Stereocontrolled syntheses of the constituent amino acids.
Figure 1. (a) UV-visible absorption spectrum of pyrimido[5,4-g]pteridine N-oxide 1 (5 X M ) in MeCN. (b) Difference spectrum of… 
Highly Cited
1986
Highly Cited
1986
Influence of Free Fatty Acids, Lysophosphatidylcholine, Platelet-Activating Factor, Acylcarnitine, and Echinocandin B on 1,3-beta-d-Glucan Synthase and Callose Synthesis.
The activity of 1,3-beta-d-glucan synthase assayed in the presence of digitonin in a microsomal preparation from suspension… 
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