Echinocandins

Known as: Echinocandins [Chemical/Ingredient], echinocandin 
Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
The CLSI established clinical breakpoints (CBPs) for caspofungin (CSF), micafungin (MCF) and anidulafungin (ANF) versus Candida… (More)
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Highly Cited
2010
Highly Cited
2010
Echinocandins are the most recent introduction to the antifungal armamentarium and target the synthesis of β-(1,3)-glucan, the… (More)
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Highly Cited
2009
Highly Cited
2009
Candida albicans is the leading fungal pathogen of humans, causing life-threatening disease in immunocompromised individuals… (More)
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Highly Cited
2008
Highly Cited
2008
Echinocandins are a new generation of novel antifungal agent that inhibit cell wall beta(1,3)-glucan synthesis and are normally… (More)
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Review
2007
Review
2007
Invasive fungal infections cause morbidity and mortality in severely ill patients, and limited drug classes restrict treatment… (More)
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Review
2006
Review
2006
Micafungin, a potent inhibitor of 1,3-beta-D-glucan synthase, has become the second available agent in the echinocandins class… (More)
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Review
2003
Review
2003
The echinocandins are large lipopeptide molecules that are inhibitors of beta-(1,3)-glucan synthesis, an action that damages… (More)
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Highly Cited
2002
Highly Cited
2002
Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance to antimicrobial agents. Evidence… (More)
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Review
2002
Review
2002
1103, p. 371. American Society for Microbiology, Washington, DC. 5. Villanueva, A., Arathoon, E. G., Gotuzzo, E., Berman, R. S… (More)
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Highly Cited
1998
Highly Cited
1998
The in vitro antifungal activities of SCH56592, MK-0991, and LY303366 against 83 isolates of Acremonium strictum, Aspergillus… (More)
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