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Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia.
TLDR
In patients undergoing chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome, posaconazoles prevented invasive fungal infections more effectively than did either fluconazole or itraconazole and improved overall survival.
ESCMID* guideline for the diagnosis and management of Candida diseases 2012: non-neutropenic adult patients.
TLDR
This part of the EFISG guidelines focuses on non-neutropenic adult patients, and liposomal amphotericin B and voriconazole are supported with moderate, and fluconazole with marginal strength for the targeted initial treatment of candidaemia.
Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia.
TLDR
Caspofungin is as effective as and generally better tolerated than liposomal amphotericin B when given as empirical antifungal therapy in patients with persistent fever and neutropenia.
European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3—2009 Update
TLDR
The goal of this paper is to summarize the new proposals from ECIL 3, based on the results of studies published after the ECIL 2 meeting, and the prophylactic recommendations for hematopoietic stem cell transplant recipients were formulated differently.
ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormycosis 2013.
TLDR
These European Society for Clinical Microbiology and Infectious Diseases and European Confederation of Medical Mycology Joint Clinical Guidelines focus on the diagnosis and management of mucormycosis and strongly recommend continuing treatment until complete response demonstrated on imaging and permanent reversal of predisposing factors.
ESCMID and ECMM joint clinical guidelines for the diagnosis and management of rare invasive yeast infections.
TLDR
Recommendations about the microbiological investigation and detection of invasive infection were made and current knowledge on the most appropriate antifungal and supportive treatment was reviewed.
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