metoprine

Known as: 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine, DDMP, methodichlorophen 
A diaminopyrimidine folate antagonist with potential antineoplastic activity. Metoprine inhibits dihydrofolate reductase, resulting in decreased… (More)
National Institutes of Health

Papers overview

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2006
2006
The bitterness of a saponin mixture (containing saponin B and DDMP (2,3-dihydro-2,5-dihydroxy-6methyl-4H-pyran-4-one) saponin in… (More)
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2005
2005
Growing interest in plant secondary metabolites has brought with it the need for economical, rapid and efficient extraction… (More)
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2004
2004
Diabetes disease management programs (DDMPs) are proliferating, but their effectiveness in improving quality and mitigating… (More)
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2000
2000
An extract was prepared from a commercial soybean-processing by-product (soybean molasses) and was fractionated into purified… (More)
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Review
1998
Review
1998
Saponins can be found in more than one hundred plant families and in some marine animals. However, chemical investigation of… (More)
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1997
1997
Aqueous solution of glucose and glycine was heated under reflux for 4 h and extracted with ethyl acetate. Reversed phase HPLC of… (More)
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1992
1992
We examined the effects of (S)-alpha -fluoromethylhistidine (FMH), an inhibitor of histidine decarboxylase, and metoprine, an… (More)
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1986
1986
To study the extent to which histamine methylation accounts for the biosynthesis of histamine metabolites in brain, the effects… (More)
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1984
1984
Methotrexate (MTX)-resistant human breast cancer cells (MTXR ZR-75) were obtained following serial passage of the wild-type ZR-75… (More)
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1983
1983
Methotrexate (MTX)-resistant sublines of malignant human cells were selected in vitro by stepwise increase in drug concentration… (More)
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