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The use of antihistamines (AHs) has been associated with cognitive and psychomotor impairments, largely caused by the sedative… Expand AIMS
Previous studies have demonstrated that the antihistamines mequitazine, cetirizine and dexchlorpheniramine produce mild… Expand Background Mequitazine is a so‐called ‘non‐sedative’ second‐generation antihistamine even though it has never been firmly… Expand SYNOPSIS
Cetirizine, the carboxylated metabolite of hydroxyzine, is a specific and long-acting histamine H1-receptor antagonist… Expand Cetirizine, a piperazine derivative and carboxylated metabolite of hydroxyzine, is a potent histamine H1-receptor antagonist with… Expand Terfenadine is a selective histamine H1-receptor antagonist which, in pharmacodynamic studies, is devoid of central nervous… Expand Loratadine is a long-acting H1 antagonist devoid of anticholinergic and sedative effects. A double-blind, placebo-controlled… Expand Terfenadine is a selective H1-histamine receptor antagonist. The lack of significant terfenadine penetration into the CNS is… Expand Astemizole is an H1-histamine receptor antagonist with a long duration of action permitting once daily administration. Its… Expand Oxatomide is an orally active H1-histamine receptor antagonist which, as appears to occur with some other antihistamines, also… Expand