Phenothiazines

Known as: Phenothiazines [Chemical/Ingredient] 
Compounds containing dibenzo-1,4-thiazine. Some of them are neuroactive.
National Institutes of Health

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10-piperazinylpropylphenothiazine3,7-diaminophenothiazin-5-iumBN 82204LM 24056
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ChlorpromazineChlorpromazine hydrochloride 100 MG Oral TabletFluphenazineFluphenazine enanthate
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Papers overview

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Highly Cited
2012
Highly Cited
2012
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Proteolytic activity of the mucosa-associated lymphoid tissue lymphoma translocation protein-1 (MALT1) paracaspase is required… (More)
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Highly Cited
2005
Highly Cited
2005
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins.
Tau protein is the major component of the intraneuronal filamentous inclusions that constitute defining neuropathological… (More)
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2004
2004
NMR-based characterization of phenothiazines as a RNA binding scaffold.
Phenothiazines were identified by virtual screening as promising ligands for HIV-1 TAR RNA and A-site ribosomal RNA, and binding… (More)
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Highly Cited
2004
Highly Cited
2004
The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action.
The differential transcriptional response of Mycobacterium tuberculosis to drugs and growth-inhibitory conditions was monitored… (More)
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Highly Cited
2003
Highly Cited
2003
Phenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus.
Efflux-related multidrug resistance (MDR) is a significant means by which bacteria can evade the effects of selected… (More)
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Review
2000
Review
2000
Prevention and Treatment of Postoperative Nausea and Vomiting
Pain, nausea and vomiting are frequently listed by patients as their most important perioperative concerns. With the change in… (More)
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Highly Cited
1996
Highly Cited
1996
Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines.
In Alzheimer disease (AD) the microtubule-associated protein tau is redistributed exponentially into paired helical filaments… (More)
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Highly Cited
1996
Highly Cited
1996
Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs.
Tritiated haloperidol and tritiated dopamine label postsynaptic dopamine receptors in mammalian brain. Clinical potencies of… (More)
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Highly Cited
1975
Highly Cited
1975
Neocortical and hippocampal activation relation to behavior: effects of atropine, eserine, phenothiazines, and amphetamine.
Evidence is presented to suggest that the hippocampus receives 2 nonspecific inputs from the brainstem, each capable of producing… (More)
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Highly Cited
1975
Highly Cited
1975
Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons.
Neuroleptic (antipsychotic) drugs inhibited the electrically stimulated release of [3-H] dopamine from rat striatal slices. The… (More)
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