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10-piperazinylpropylphenothiazine

Known as: 10-(3-(1-piperazinyl)propyl)-10H-phenothiazine, demethylperazine, desmethylperazine 
National Institutes of Health

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Broader (1)

Phenothiazines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Single-dose kinetics of the neuroleptic drug perazine in psychotic patients
Eight male and two female unmedicated psychotic patients received 100 mg perazine orally and seven blood samples were taken… 
1989
1989
Monitoring of Serum Bioactivity Levels of Perazine and its Metabolites by Radioreceptor Assay
The bioactivity of perazine and its metabolites in human serum was analysed by radioreceptor assay. The IC50 value (the… 
1989
1989
Pharmacological Studies on Perazine and its Primary Metabolites
The study served to answer the question whether metabolites possibly contribute to the clinical actions of the neuroleptic drug… 
Highly Cited
1986
Highly Cited
1986
Substrate specificity of the rabbit lung flavin-containing monooxygenase for amines: oxidation products of primary alkylamines.
Substrate activity of a flavin-containing monooxygenase isolated from rabbit lung microsomes has been examined with a number of… 
1983
1983
Prediction and evaluation criteria in perazine therapy of acute schizophrenics. Methodological considerations, sample population, and research variables.
In an open study of schizophrenic patients treated with perazine (Taxilan), a multidimensional approach comprising the following… 
1980
1980
High affinity binding of perazine and desmethylperazine to human alpha 1-acid glycoprotein.
1980
1980
Reliable routine method for determination of perazine in serum by thin-layer chromatography with an internal standard.
1980
1980
Possible mutagenicity of the psychoactive phenothiazine derivative perazine in vivo and in vitro
SummaryHuman lymphocyte cultures from 55 schizophrenic subjects and one manic-depressive subject being treated with the… 
1977
1977
Kinetics of 35S-perazine in the bile fistula rat
SummaryAnesthetized male rats with a bile fistula received 25 mg/kg 35S-labeled perazine (Per) i.p. and bile fractions were… 
1976
1976
Structure-activity relationships among desmethyl derivatives of neuroleptics and antidepressants for substrate specificty to indolethylamine N-methyltransferase from rabbit lung.
Desmethylperazine (norperazine) and desmethylprochlorperazine (norprochlorperazine), like nor1- and nor2chlorpromazine, are… 
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