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Chlorpromazine

Known as: Chlorpromazinum, Chloropromazine, 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine 
A phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine exerts its antipsychotic effect by blocking… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (18)

7,8-dihydroxychlorpromazine7,8-dioxochlorpromazineAminazineChlordelazine

Broader (8)

Adrenergic AgentsAminesAntiemeticsAntihypertensive Agents
Adrenergic alpha-Antagonists [MoA]Anxiety DisordersAttention Deficit and Disruptive Behavior DisordersChlorpromazine hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1985
Highly Cited
1985
Characterization of octopamine-sensitive adenylate cyclase: elucidation of a class of potent and selective octopamine-2 receptor agonists with toxic effects in insects.
Octopamine-2 receptors, associated with activation of adenylate cyclase, mediate a number of the important hormonal and… 
Highly Cited
1982
Highly Cited
1982
Psychological effects of buspirone.
Chief among the drawbacks of the benzodiazepines is the risk of a withdrawal syndrome when the drugs are discontinued after… 
1979
1979
In vitro metabolism and activation of carcinogenic aromatic amines by subcellular fractions of human liver.
Abstract In vitro metabolism and metabolic activation of 2-acetylaminofluorene (AAF), 2-aminofluorene, and 2,4-diaminoanisole to… 
1979
1979
Effect of structure on phenothiazine cation radical reactions in aqueous buffers.
The reactions of the cation radicals of 11 phenothiazine tranquilizers were examined in mildly acidic aqueous buffers. Of the 11… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
Highly Cited
1975
Highly Cited
1975
Comparative Hemodynamic Responses to Chlorpromazine, Nitroprusside, Nitroglycerin, and Trimethaphan Immediately After Open‐Heart Operations
The hemodynamic effects of intravenous chlorpormazine, nitroprusside, nitroglycerin, and trimethaphan camsylate were studied in… 
Highly Cited
1970
Highly Cited
1970
Factors affecting chlorpromazine plasma levels in psychiatric patients.
IT RECENTLY became possible to Measure concentrations of chlorpromazine and some of its relatively nonpolar metabolites in the… 
1969
1969
Effects of Chlorpromazine in Patients with Hepatic Disease
Patients with cirrhosis were found to be extremely sensitive to chlorpromazine as shown by slowing of the electroencephalograph… 
Highly Cited
1956
Highly Cited
1956
Postanesthetic nausea, vomiting, and retching; evaluation of the antiemetic drugs dimenhydrinate (dramamine), chlorpromazine, and pentobarbital sodium.
• The antiemetic possibilities of three drugs were studied in 554 surgical patients who were divided into five groups by using a… 
1955
1955
Obstructive-type jaundice due to chlorpromazine (thorazine); report of three cases.
Chlorpromazine (Thorazine) (10-[γ-dimethylaminopropyl]-2-chlorophenothiazine hydrochloride) has become an extremely popular and… 
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