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Chlorpromazine

Known as: Chlorpromazinum, Chloropromazine, 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine 
A phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine exerts its antipsychotic effect by blocking… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (18)

7,8-dihydroxychlorpromazine7,8-dioxochlorpromazineAminazineChlordelazine

Broader (8)

Adrenergic AgentsAminesAntiemeticsAntihypertensive Agents
Adrenergic alpha-Antagonists [MoA]Anxiety DisordersAttention Deficit and Disruptive Behavior DisordersChlorpromazine hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1982
Highly Cited
1982
Psychological effects of buspirone.
Chief among the drawbacks of the benzodiazepines is the risk of a withdrawal syndrome when the drugs are discontinued after… 
Highly Cited
1977
Highly Cited
1977
Factors controlling the activities of phosphatidate phosphohydrolase and phosphatidate cytidylyltransferase. The effects of chlorpromazine, demethylimipramine, cinchocaine, norfenfluramine…
1. Microsomal membranes from rat liver were incubated with ATP, CoA, Mg2+, [14C]palmitate, F- and sn-glycerol 3-phosphate in… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
Highly Cited
1975
Highly Cited
1975
Comparative Hemodynamic Responses to Chlorpromazine, Nitroprusside, Nitroglycerin, and Trimethaphan Immediately After Open‐Heart Operations
The hemodynamic effects of intravenous chlorpormazine, nitroprusside, nitroglycerin, and trimethaphan camsylate were studied in… 
1971
1971
On the mechanism of chlorpromazine-induced histamine release from rat mast cells.
On exposure to chlorpromazine in concentrations above 20 μM, histamine was released by rat mast cells in vitro. Histamine release… 
1965
1965
Surface activity of chlorpromazine and chlorpromazine sulfoxide in the presence of insoluble monomolecular films.
The surface activity of chlorpromazine and its sulfoxide has been investigated at interfaces covered with insoluble monomolecular… 
1958
1958
Temperature response of the rat to action and interaction of chlorpromazine, reserpine and serotonin.
Reserpine was found to cause a prolonged increase in oxygen consumption while chlorpromazine and serotonin produced a comparable… 
1957
1957
Inhibitory effect of chlorpromazine upon the adrenal cortical response to insulin hypoglycemia in man.
The large number of recent publications concerning the inter-relationships between the central nervous system and the anterior… 
1956
1956
Complications of chlorpromazine therapy.
1. Chlorpromazine has many undesirable effects, most of which are transient and of relatively minor clinical significance. 2… 
1954
1954
The anti-emetic activity of 10-(gamma-dimethylaminopropyl)-2-chlorophenothiazine (chlorpromazine) in dog and cat.
Chlorpromazine, 10-(γ-dimethylaminopropyl)-2-chlorophenothiazine hydro-chloride, a non-antihistaminic congener of Phenergan, was…