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The question of which antipsychotic drug should be preferred for the treatment of schizophrenia is controversial, and… Expand BACKGROUND
The historical process of discovery and clinical introduction of chlorpromazine, one of the greatest advances of 20th… Expand Therapeutic regimens that comprise more than one active ingredient are commonly used in clinical medicine. Despite this, most… Expand BACKGROUND
Several clinical and research applications require an estimation of therapeutic dose equivalence across antipsychotic… Expand The purported advantages of second-generation or ‘atypical’ antipsychotics relative to first-generation antipsychotics have not… Expand Background: Al though the prin ci pal brain tar get that all an tipsy chotic drugs at tach to is the do pamine D2 re cep tor, tra… Expand OBJECTIVE
The purpose of this study was to examine the efficacy and side effects of haloperidol, chlorpromazine, and lorazepam… Expand The treatment of schizophrenic patients who fail to respond to adequate trials of neuroleptics is a major challenge. Clozapine… Expand A 41-residue peptide purified as a corticotropin-releasing factor/beta-endorphin-releasing factor (CRF) in vitro was tested for… Expand