luzopeptin
National Institutes of Health
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A novel cyclic peptide has been designed from several potent marine cytotoxic peptides, including IB-01212, luzopeptin, triostin…
A bifunctional intercalates may intercalate with DMAin at least two ways. Both intercalating moieties may intercalate with the…
Abstract The luzopeptin antibiotics contain a cyclic decadepsipeptide to which are attached two quinoline chromophores that…
The in vitro sensitivity of Plasmodium falciparum to bleomycin, busulfan, camptothecin, CC-1065, cisplatin, daunomycin…
Imino proton exchange studies are reported on the complexes formed by bisintercalation of luzopeptin around the two central A.T…
We have examined the binding of luzopeptin, an antitumor antibiotic, to five DNA fragments of varying base composition. The drug…
The depsipeptide DNA-intercalating antibiotic luzopeptin was studied in solution by n.m.r. methods. Two-dimensional 1H double…
Luzopeptin analogues, A, B and C (in decreasing degree of acetylation) were active, less active and inactive, respectively…