lubeluzole
National Institutes of Health
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Lubeluzole [(S)-9] has been synthesized by a convergent synthesis, alkylation of N-methyl-N-piperidin-4-yl-1,3-benzothiazol-2…
Lubeluzole [S-4-(2-benzothiazolylmethylamino)-α-((3,4-difluorophenoxy)methyl)-1-piperidineethanol] reduces the severity of…
Background and Purpose —This trial was a double-blind, placebo-controlled, phase III trial with an 8-hour inclusion window to…
Lubeluzole, a novel nitric oxide synthase (NOS) pathway modulator, was shown to be neuroprotective in cerebral ischemia as…
Background and Purpose Lubeluzole is a novel benzothiazole compound that has shown neuroprotective activity in preclinical models…
BACKGROUND AND PURPOSE
We aimed to assess the safety and efficacy of lubeluzole in patients with a clinical diagnosis of acute…
The cardiovascular effects of the antihypoxic and neuroprotective drug, lubeluzole, were investigated using beagle dogs…