lomefloxacin

Known as: LFLX, Lomefloxacinum, (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid 
A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
020406019882018

Papers overview

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2002
2002
A total of 182 patients with chronic bacterial prostatitis (CBP) were recruited into this multicentre prospective, randomized… (More)
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2000
2000
The efficacy and safety of three oral fluoroquinolones (lomefloxacin, levofloxacin, and ciprofloxacin) for the treatment of… (More)
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1998
1998
OBJECTIVES To evaluate, in two randomized, multicenter trials, levofloxacin compared with ciprofloxacin and lomefloxacin for… (More)
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1995
1995
The susceptibilities of 45 strains of Neisseria gonorrhoeae, including 25 strains susceptible to ciprofloxacin (MICs, < or = 0.06… (More)
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Highly Cited
1993
Highly Cited
1993
We examined the impact of dose fractionation and altered MICs on survivorship in a neutropenic rat model of Pseudomonas… (More)
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1992
1992
The penetration of lomefloxacin into human polymorphonuclear leukocytes (PMNs) and peritoneal macrophages (PMphis) was evaluated… (More)
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1992
1992
We report the results of scarified photopatch testing in 3 patients with photosensitivity to lomefloxacin, a new quinolone… (More)
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1990
1990
The inhibition of supercoiling activity of reconstituted Escherichia coli DNA gyrase by lomefloxacin, ciprofloxacin, and… (More)
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1989
1989
Enoxacin and lomefloxacin were found to display a biphasic response when their bactericidal activities were investigated… (More)
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1988
1988
The pharmacokinetics of five dose levels of lomefloxacin (100, 200, 400, 600, and 800 mg) were examined in a single-dose, double… (More)
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