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Quinolone Antibacterial Agents

Known as: [AM400] QUINOLONES, QUINOLONE ANTIBACTERIALS, Quinolones 
National Institutes of Health

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24 HR Ciprofloxacin 500 MG Extended Release Oral Tablet4-QuinolonesBAYTRILCiprofloxacin 500 MG Oral Tablet
Quinolone Antibacterial [EPC]Quinolones

Papers overview

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Highly Cited
2009
Highly Cited
2009
In Vitro Activity of Nemonoxacin, a Novel Nonfluorinated Quinolone, against 2,440 Clinical Isolates
ABSTRACT The in vitro activity of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, was tested against 2,440 clinical… 
Review
2007
Review
2007
In vivo diagnostic tests in adverse reactions to quinolones.
BACKGROUND AND OBJECTIVE Contradictory reports of the sensitivity of skin tests in quinolone allergy have been reported. Our… 
2005
2005
Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation.
OBJECTIVES Quinolone derivatives have been shown to inhibit human immunodeficiency virus (HIV) replication at the transcriptional… 
Highly Cited
2002
Highly Cited
2002
On the effect of covalently appended quinolones on termini of DNA duplexes.
Quinolones are gyrase inhibitors that are widely used as antibiotics in the clinic. When covalently attached to oligonucleotides… 
Highly Cited
1998
Highly Cited
1998
Inter- and Intraquinolone Predictors of Antimicrobial Effect in an In Vitro Dynamic Model: New Insight into a Widely Used Concept
ABSTRACT Earlier efforts to search for pharmacokinetic and bacteriological predictors of fluoroquinolone antimicrobial effects… 
1997
1997
Quinolone susceptibility of norA-disrupted Staphylococcus aureus
The MIC of norfloxacin for the norA-disrupted mutant termed RDN1, obtained from quinolone-susceptible Staphylococcus aureus… 
Highly Cited
1988
Highly Cited
1988
In vitro activity of PD 127,391, an enhanced-spectrum quinolone
The in vitro activity of PD 127,391, a dihalogenated quinolone, was compared with those of ofloxacin, ciprofloxacin, nalidixic… 
Highly Cited
1988
Highly Cited
1988
Pharmacokinetics and tissue penetration of orally administered lomefloxacin
The pharmacokinetics of the quinolone lomefloxacin were determined following a single 400-mg oral dose given to each of six male… 
Highly Cited
1988
Highly Cited
1988
Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12
Quinolone antimicrobial agents are known to interact with DNA gyrase, but the mechanism by which bacterial cell death occurs is… 
Highly Cited
1987
Highly Cited
1987
In vitro and in vivo activity of NY-198, a new difluorinated quinolone
NY-198 [1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3- quinolinecarboxylic acid hydrochloride] is a new… 
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