linezolid

Known as: N-((3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide, Linezolide, Linezolid [Chemical/Ingredient] 
A synthetic oxazolidinone derivative, Linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
020040019912017

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND Post hoc analyses of clinical trial data suggested that linezolid may be more effective than vancomycin for treatment… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Linezolid has antimycobacterial activity in vitro and is increasingly used for patients with highly drug-resistant… (More)
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Highly Cited
2007
Highly Cited
2007
Linezolid, which targets the ribosome, is a new synthetic antibiotic that is used for treatment of infections caused by Gram… (More)
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Highly Cited
2005
Highly Cited
2005
Skin and soft tissue infections (SSTIs) are a common cause of morbidity in both the community and the hospital. An SSTI is… (More)
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Highly Cited
2004
Highly Cited
2004
We evaluated the impact of high (9.5 log10 CFU/g) and moderate (5.5 log10 CFU/g) inocula of methicillin-susceptible and… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE To assess the effect of baseline variables, including treatment, on outcome in patients with nosocomial pneumonia due… (More)
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Highly Cited
2002
Highly Cited
2002
Linezolid, the first available member of a new antibiotic class, the oxazolidinones, is broadly active against gram-positive… (More)
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Highly Cited
2002
Highly Cited
2002
In this study, our objective was to determine the steady-state intrapulmonary concentrations and pharmacokinetic parameters of… (More)
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Highly Cited
2001
Highly Cited
2001
Linezolid, the first oxazolidinone, is active against gram-positive bacteria, including multidrug-resistant strains. This… (More)
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Highly Cited
2001
Highly Cited
2001
Linezolid is a new oxazolidinone antibiotic used to treat infections caused by vancomycin-resistant enterococci (VRE). In early… (More)
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