U 100766

Linezolid, the first oxazolidinone, is active against gram-positive bacteria, including multidrug-resistant strains. This… (More)

This randomized, double-blind, multicenter trial compared the efficacy and safety of linezolid, an oxazolidinone, with those of… (More)

The in-vitro activity of linezolid, a novel oxazolidinone, was investigated in comparison with those of amoxycillin, cefuroxime… (More)

The activities of the oxazolidinone antibacterial agents eperezolid (PNU-100592) and linezolid (PNU-100766) were compared with… (More)

U-100592 and U-100766 are closely related antibiotics of the oxazolidinone class. Their in vitro activities were determined… (More)

The oxazolidinones are a new class of synthetic antibiotics with good activity against gram-positive pathogenic bacteria… (More)

Oxazolidinones make up a relatively new class of antimicrobial agents which possess a unique mechanism of bacterial protein… (More)

The Upjohn oxazolidinones, U-100592 and U-100766, are orally bioavailable synthetic antimicrobial agents with spectra of activity… (More)

Two new fluorinated oxazolidinones, U-100592 and U-100766, were evaluated against more than 659 gram-positive and -negative… (More)

Bacterial resistance development has become a very serious clinical problem for many classes of antibiotics. The 3-aryl-2… (More)