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U 100766

Known as: PNU-100766, PNU100766, PNU 100766 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

linezolid

Papers overview

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Review
2002
Review
2002
Linezolid: The First Oxazolidinone Antimicrobial
Each antimicrobial agent developed for clinical use during the past 60 years has ultimately encountered problems with the… 
Highly Cited
2002
Highly Cited
2002
Cerebrospinal Fluid Linezolid Concentrations in Postneurosurgical Central Nervous System Infections
Gram-positive (GP) cocci, mainly methicillin-resistant staphylococci, are the most frequent pathogens involved in central nervous… 
Highly Cited
1998
Highly Cited
1998
The in-vitro activity of linezolid (U-100766) and tentative breakpoints.
The in-vitro activity of linezolid, a novel oxazolidinone, was investigated in comparison with those of amoxycillin, cefuroxime… 
Review
1998
Review
1998
In vitro antibiotic synergy against Flavobacterium meningosepticum: implications for therapeutic options.
Flavobacterium meningosepticum is an unusual, highly resistant, gram-negative bacillus that is associated with neonatal… 
Highly Cited
1998
Highly Cited
1998
Comparative In Vitro Activities and Postantibiotic Effects of the Oxazolidinone Compounds Eperezolid (PNU-100592) and Linezolid (PNU-100766) versus Vancomycin against Staphylococcus aureus, Coagulase…
ABSTRACT The activities of the oxazolidinone antibacterial agents eperezolid (PNU-100592) and linezolid (PNU-100766) were… 
Highly Cited
1997
Highly Cited
1997
In vitro activities of the oxazolidinone antibiotics U-100592 and U-100766 against Staphylococcus aureus and coagulase-negative Staphylococcus species
U-100592 and U-100766 are closely related antibiotics of the oxazolidinone class. Their in vitro activities were determined… 
Highly Cited
1996
Highly Cited
1996
In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents
Oxazolidinones make up a relatively new class of antimicrobial agents which possess a unique mechanism of bacterial protein… 
Highly Cited
1996
Highly Cited
1996
Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.
Bacterial resistance development has become a very serious clinical problem for many classes of antibiotics. The 3-aryl-2… 
Highly Cited
1996
Highly Cited
1996
In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections
The Upjohn oxazolidinones, U-100592 and U-100766, are orally bioavailable synthetic antimicrobial agents with spectra of activity… 
Highly Cited
1996
Highly Cited
1996
In vitro antimicrobial activities and spectra of U-100592 and U-100766, two novel fluorinated oxazolidinones
Two new fluorinated oxazolidinones, U-100592 and U-100766, were evaluated against more than 659 gram-positive and -negative… 
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