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levothyroxine

Known as: T4, T4 Thyroid Hormone, L-T4 
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of… 
National Institutes of Health

Related topics

Related topics

42 relations

Broader (2)

Amino Acids, CyclicThyroid Hormones

Narrower (18)

DextrothyroxineEferoxEltroxinEltroxine
GoiterHyperthyroxinemiaHypothyroidismIn Blood

Papers overview

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Highly Cited
1978
Highly Cited
1978
The effects of cortisol, corticotropin and thyroxine on the synthesis of glycerolipids and on the phosphatidate phosphohydrolase activity in rat liver.
1. Male rats were injected daily for 5 days with 0.15m-NaCl, corticotropin, cortisol or l-thyroxine and the rates of glycerolipid… 
Highly Cited
1976
Highly Cited
1976
Radioimmunoassay of thyrotrophin releasing hormone in human serum and its clinical application.
A radioimmunoassay for thyrotrophin releasing hormone (TRH) in human serum is described. Inactivation of TRH immunoreactivity by… 
Highly Cited
1976
Highly Cited
1976
Thyroxine-protein interactions. Interaction of thyroxine and triiodothyronine with human thyroxine-binding globulin.
The effect of temperature on the binding of thyroxine and triiodothyronine to thyroxine-binding globulin has been studied by… 
Highly Cited
1974
Highly Cited
1974
Inhibition of thyrotropin and prolactin secretions in primary hypothyroidism by 2-Br-alpha-ergocryptine.
ABSTRACT A single oral dose of the ergot alkaloid, 2-Br-a-ergocryptine (CB-154) (1.25 to 5 mg) caused a significant decrease… 
Highly Cited
1974
Highly Cited
1974
Effects on the pituitary-thyroid axis and prolactin secretion of single and repetitive oral doses of thyrotropin-releasing hormone (TRH).
ABSTRACT The effects of single and repetitive oral doses of synthetic TRH were studied in healthy young men and women… 
Highly Cited
1972
Highly Cited
1972
Extrathyroidal conversion of thyroxine to triiodothyronine in sheep.
A study of in vivo extrathyroidal conversion of thyroxine (T4) to triiodothyronine (T3) has been conducted in sheep using a newly… 
Highly Cited
1970
Highly Cited
1970
Specific Antibodies to Triiodothyronine Hormone
WE have been able to stimulate the formation in rabbits of a very specific antibody against triiodothyronine (T3) by injecting… 
Highly Cited
1963
Highly Cited
1963
Thyroid function and the cardiac disposition of catecholamines.
Hyperthyroid rats show an elevated and prolonged hemodynamic response to injected epinephrine; hypothyroid rats have lower base… 
Highly Cited
1962
Highly Cited
1962
The effect of thyroxine on isolated dehydrogenases. II. Sedimentation changes in glutamic dehydrogenase.
Highly Cited
1956
Highly Cited
1956
An unusual iodinated protein of the serum in Hashimoto's thyroiditis.
Protein-bound iodine may exist in forms other than thyroxine. Man and associates (1) found that patients receiving Lugol’s…