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levothyroxine

Known as: T4, T4 Thyroid Hormone, L-T4 
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of… 
National Institutes of Health

Related topics

Related topics

42 relations

Broader (2)

Amino Acids, CyclicThyroid Hormones

Narrower (18)

DextrothyroxineEferoxEltroxinEltroxine
GoiterHyperthyroxinemiaHypothyroidismIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1985
Highly Cited
1985
Molecular interactions of toxic chlorinated dibenzo-p-dioxins and dibenzofurans with thyroxine binding prealbumin.
The interactions of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds with prealbumin, a model for the nuclear thyroid… 
Highly Cited
1982
Highly Cited
1982
Computer graphics in drug design: molecular modeling of thyroid hormone-prealbumin interactions.
Computer graphics modeling of the thyroxine-prealbumin complex provides a detailed picture of the interactions between thyroxine… 
Highly Cited
1980
Highly Cited
1980
Fetal lung in organ culture. III. Comparison of dexamethasone, thyroxine, and methylxanthines.
Exposure of explants of fetal rat lung to dexamethasone, thyroxine, or the methylxanthines, aminophylline and caffeine, resulted… 
Highly Cited
1978
Highly Cited
1978
Sulfhydryl groups and the monodeiodination of thyroxine to triiodothyronine.
Sulfhydryl reagents exert a profound influence on the monodeiodination of thyroxine to triiodothyronine by rat and sheep tissues… 
Highly Cited
1977
Highly Cited
1977
Influence of combinations of bovine growth hormone, 17 alpha-methyltestosterone, and L-thyroxine on growth of yearling coho salmon (Oncorhynchus kisutch).
Groups of yearling coho salmon held at 10 °C on a natural photoperiod, and fed excess ration daily, were administered either… 
Highly Cited
1976
Highly Cited
1976
Alteration in intracellular sodium concentration and ouabain-sensitive ATPase in erythrocytes from hyperthyroid patients.
The activity of the ouabain-sensitive sodium-potassium-activated component of the ATP-hydrolyzing enzyme system (ouabain… 
Highly Cited
1968
Highly Cited
1968
Decreased serum free thyroxine concentration in patients treated with diphenylhydantoin.
ABSTRACT When diphenylhydantoin is added to serum in vitro the free thyroxine fraction increases. The apparent magnitude of this… 
Highly Cited
1963
Highly Cited
1963
Thyroid function and the cardiac disposition of catecholamines.
Hyperthyroid rats show an elevated and prolonged hemodynamic response to injected epinephrine; hypothyroid rats have lower base… 
Highly Cited
1960
Highly Cited
1960
The properties of thyroglobulin. I. The effects of alkali.
Several studies have appeared in the past 25 years (l-5) concerning the physicochemical properties of thyroglobulin, the protein… 
Highly Cited
1958
Highly Cited
1958
Chromatography of serum proteins in normal and pathologic sera: the distribution of protein-bound carbohydrate and cholesterol, siderophilin, thyroxin-binding protein, B12-binding protein, alkaline…
Chromatographic techniques have recently been introduced which provide new approaches to serum protein separation and… 
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