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levodopa methyl ester

Known as: L-dopa methyl ester, MELEVODOPA, methyl L-dopa 
National Institutes of Health

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5 relations

Broader (2)

Antiparkinson AgentsLevodopa
Methyldopaanalogs & derivatives

Narrower (1)

levodopa methyl ester hydrochloride

Papers overview

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2009
2009
Homology modeling of adenosine A2A receptor and molecular docking for exploration of appropriate potent antagonists for treatment of Parkinson's disease.
Parkinson's disease (PD) is a neurodegenerative disorder of central nervous system (CNS) that impaired the patient motor skills… 
2006
2006
Determination, purity assessment and chiral separation of levodopa methyl ester in bulk and formulation pharmaceuticals.
A sensitive, reliable and reproducible HPLC method with electrochemical detection (HPLC-ECD) has been developed for the… 
2005
2005
Determination of levodopa methyl ester and its metabolites in rat serum by CZE with amperometric detection
AbstractA reliable and reproducible method, capillary zone electrophoresis with amperometric detection (CZE–AD), has been… 
1996
1996
Fluctuating parkinsonism: a pilot study of single afternoon dose of levodopa methyl ester
Thirty-four patients with idiopathic fluctuating Parkinson's disease and early afternoon “delayed on” or severely resistant “off… 
Highly Cited
1994
Highly Cited
1994
Comparison between a fast and a slow release preparation of levodopa and a combination of the two: a clinical and pharmacokinetic study.
After overnight drug withdrawal and in the fasting state, 11 patients with Parkinson's disease (PD) and a fluctuating response to… 
1994
1994
The clinical efficacy of a single afternoon dose of levodopa methyl ester: a double-blind cross-over study versus placebo.
Levodopa methyl ester (LDME) is a highly water soluble derivative produced by esterification of the carboxilic acid moiety of the… 
1991
1991
The Clinical Efficacy of Oral Levodopa Methyl Ester Solution in Reversing Afternoon “Off” Periods in Parkinson's Disease
SummaryWe compared the efficacy of a single dose of an oral solution of levodopa methyl ester (ME) to that of standard levodopa… 
1991
1991
Subcutaneous and sublingual levodopa methyl ester in Parkinson's disease.
1 Stibe CMH, Lees AJ, Kempster PA, Stern GM. Subcutaneous apomorphine in parkinsonian on-off oscillations. Lancet 1988;i:403-6. 2… 
1983
1983
Sodium ascorbate enhancement of carbidopa-levodopa methyl ester antitumor activity against pigmented B16 melanoma.
We report here the single and combined antitumor activity on B16 melanoma in female C57BL/6 X DBA/2F1 mice bearing s.c. tumors of… 
1982
1982
Dietary influence of tyrosine and phenylalanine on the response of B16 melanoma to carbidopa-levodopa methyl ester chemotherapy.
Abstract The effect of dietary tyrosine and phenylalanine on survival of adult female C57BL/6 × DBA/2 F, mice bearing i.p. slow… 
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