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Levodopa

Known as: beta-(3,4-Dihydroxyphenyl)-L-alanine, 3,4-Dihydroxy-L-phenylalanine, .beta.-(3,4-Dihydroxyphenyl)-L-alanine 
An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Parkinson disease (PD) treatment options have conventionally focused on dopamine replacement and provision of symptomatic relief… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Neurostimulation of the subthalamic nucleus reduces levodopa-related motor complications in advanced Parkinson's… Expand
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Review
2005
Review
2005
The dementia with Lewy bodies (DLB) Consortium has revised criteria for the clinical and pathologic diagnosis of DLB… Expand
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Highly Cited
2003
Highly Cited
2003
Preclinical studies suggest ropinirole (a D2/D3 dopamine agonist) may be neuroprotective in Parkinson's disease (PD), and a pilot… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced… Expand
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Highly Cited
2001
Highly Cited
2001
Neural responses accompanying anticipation and experience of monetary gains and losses were monitored by functional magnetic… Expand
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Review
2001
Review
2001
Involuntary movements — or dyskinesias — are a debilitating complication of levodopa therapy for Parkinson's disease that is… Expand
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Highly Cited
2000
Highly Cited
2000
Background There is debate about whether the initial treatment for patients with Parkinson's disease should be levodopa or a… Expand
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Highly Cited
2000
Highly Cited
2000
CONTEXT Pramipexole and levodopa both ameliorate the motor symptoms of early Parkinson disease (PD), but no controlled studies… Expand
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Review
2000
Review
2000
Parkinson's disease (PD) is an age-related neurodegenerative disorder with an average onset age of 60 years. In the United States… Expand
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