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Levodopa

Known as: beta-(3,4-Dihydroxyphenyl)-L-alanine, 3,4-Dihydroxy-L-phenylalanine, .beta.-(3,4-Dihydroxyphenyl)-L-alanine 
An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (18)

2,4,5-trihydroxyphenylalanine quinone2,4-dihydroxyphenylalanine3,4,6-trihydroxyphenylalanine quinone3-O-methyl-6-fluoro-dopa

Broader (2)

Antiparkinson AgentsDopa
Carbidopa / LevodopaCarbidopa 10 MG / Levodopa 100 MG Disintegrating Oral TabletCarbidopa 10 MG / Levodopa 100 MG Oral TabletCarbidopa 10 MG / Levodopa 100 MG Oral Tablet [Sinemet]

Papers overview

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2009
2009
Further studies on the mode of action of amantadine.
The anti-Parkinson agent amantadine, when administered to rats and mice, was found to cause increased motor activity in mice, and… 
2008
2008
In vitro clonal propagation of Mucuna pruriens var. utilis and its evaluation of genetic stability through RAPD markers
The Mucuna pruriens var. utilis is an important legume cover crop. Almost all the parts of the plant are reported to contain L-3… 
Highly Cited
1991
Highly Cited
1991
Pituitary Evaluation and Growth Hormone Treatment in Prader-Willi Syndrome
Short stature, obesity, hypogonadism and intellectual impairment are the main characteristics of children with Prader-Willi… 
Highly Cited
1986
Highly Cited
1986
Molecular forms of human growth hormone secreted in vivo: nonspecificity of secretory stimuli.
Several molecular forms of human GH (hGH) are present in blood, but their individual regulation is largely unknown. To examine… 
1986
1986
Effect of ovarian steroids to stimulate region-specific hypothalamic 5-hydroxytryptamine synthesis in ovariectomized rats.
Accumulations of 5-hydroxytryptophan (5HTP) and L-dihydroxyphenylalanine (L-DOPA) following decarboxylase inhibition as indices… 
1986
1986
Titrimetric determination of catecholamines and related compounds via bromine oxidation and substitution.
A titrimetric method for the determination of 0.1–10 mg of catecholamines and related compounds as pure substances and in their… 
1984
1984
The cerebral metabolism of L-dihydroxyphenylalanine. An autoradiographic and biochemical study.
The regional cerebral distribution of carbon-14 activity was studied using autoradiography following the intravenous… 
Highly Cited
1976
Highly Cited
1976
Progesterone biosynthesis and metabolism by ovarian follicles and isolated oocytes Xenopus laevis.
Ovarian follicles of Xen opus laevis exposed to exogenous radioactive pregnenolone have been observed to synthesize radioactive… 
Highly Cited
1976
Highly Cited
1976
Influence of dopaminergic agonists and antagonists on serum prolactin concentrations in the rat.
Inhibitors of dopaminergic neurotransmission, such as reserpine (RES), given alone or combined with alpha-methyl-p-tyrosine… 
Highly Cited
1960
Highly Cited
1960
Are dihydroxphenylalanine decarboxylase and 5-hydroxytrptophan decarboxylase individual enzymes?
Using an enzyme preparation from rabbit kidney cortex, the amino acids 3,4-dihydroxyphenylalanine and 5-hydroxytryptophan were…