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Levodopa

Known as: beta-(3,4-Dihydroxyphenyl)-L-alanine, 3,4-Dihydroxy-L-phenylalanine, .beta.-(3,4-Dihydroxyphenyl)-L-alanine 
An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (18)

2,4,5-trihydroxyphenylalanine quinone2,4-dihydroxyphenylalanine3,4,6-trihydroxyphenylalanine quinone3-O-methyl-6-fluoro-dopa

Broader (2)

Antiparkinson AgentsDopa
Carbidopa / LevodopaCarbidopa 10 MG / Levodopa 100 MG Disintegrating Oral TabletCarbidopa 10 MG / Levodopa 100 MG Oral TabletCarbidopa 10 MG / Levodopa 100 MG Oral Tablet [Sinemet]

Papers overview

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Highly Cited
1986
Highly Cited
1986
Molecular forms of human growth hormone secreted in vivo: nonspecificity of secretory stimuli.
Several molecular forms of human GH (hGH) are present in blood, but their individual regulation is largely unknown. To examine… 
1984
1984
The cerebral metabolism of L-dihydroxyphenylalanine. An autoradiographic and biochemical study.
The regional cerebral distribution of carbon-14 activity was studied using autoradiography following the intravenous… 
Highly Cited
1978
Highly Cited
1978
Effect of L‐Dopa on Sympathetic Nerve Activity and Blood Pressure in the Spontaneously Hypertensive Rat
We examined the effect of L-dopa, after peripheral L-amino acid decarboxylase inhibition, on sympathetic nerve activity (SNA) and… 
Highly Cited
1976
Highly Cited
1976
Progesterone biosynthesis and metabolism by ovarian follicles and isolated oocytes Xenopus laevis.
Ovarian follicles of Xen opus laevis exposed to exogenous radioactive pregnenolone have been observed to synthesize radioactive… 
Highly Cited
1976
Highly Cited
1976
Influence of dopaminergic agonists and antagonists on serum prolactin concentrations in the rat.
Inhibitors of dopaminergic neurotransmission, such as reserpine (RES), given alone or combined with alpha-methyl-p-tyrosine… 
1976
1976
Neuroendocrine Studies of Depressive Illness*
Interest in possible neuroendocrine disturbances in endogenous depression is prompted by two lines of evidence: (1) clinical… 
Highly Cited
1972
Highly Cited
1972
L-DOPA suppression of thyrotropin-releasing hormone response in man.
ABSTRACT 500 μg of thyrotropin releasing hormone (TRH) was injected intravenously into eight Parkinsonian patients being treated… 
Highly Cited
1972
Highly Cited
1972
Inhibition of prolactin secretion and successful therapy of the Forbes-Albright syndrome with L-dopa.
Fourteen patients with galactorrhea, elevated serum prolactin levels (10–1130 ng/ml), and decreased urinary excretion of… 
Highly Cited
1960
Highly Cited
1960
Are dihydroxphenylalanine decarboxylase and 5-hydroxytrptophan decarboxylase individual enzymes?
Using an enzyme preparation from rabbit kidney cortex, the amino acids 3,4-dihydroxyphenylalanine and 5-hydroxytryptophan were… 
Highly Cited
1960
Highly Cited
1960
Serotonin Synthesis in Carcinoid Patients
RECENT investigations in our laboratories have shown that α-methyl-3,4-dihydroxy-DL-phenylalanine (α-methyl-dopa) is an effective…