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Levodopa

Known as: beta-(3,4-Dihydroxyphenyl)-L-alanine, 3,4-Dihydroxy-L-phenylalanine, .beta.-(3,4-Dihydroxyphenyl)-L-alanine 
An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (18)

2,4,5-trihydroxyphenylalanine quinone2,4-dihydroxyphenylalanine3,4,6-trihydroxyphenylalanine quinone3-O-methyl-6-fluoro-dopa

Broader (2)

Antiparkinson AgentsDopa
Carbidopa / LevodopaCarbidopa 10 MG / Levodopa 100 MG Disintegrating Oral TabletCarbidopa 10 MG / Levodopa 100 MG Oral TabletCarbidopa 10 MG / Levodopa 100 MG Oral Tablet [Sinemet]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Quantitative PET studies in pretreated melanoma patients: a comparison of 6-[18F]fluoro-L-dopa with 18F-FDG and (15)O-water using compartment and noncompartment analysis.
UNLABELLED The purpose of the study was to evaluate the 6-[18F]fluoro-L-dopa (FDOPA) kinetics with PET in patients with treated… 
Highly Cited
1976
Highly Cited
1976
STRUCTURE‐ACTIVITY RELATIONS OF EXCITATORY AMINO ACIDS ON FROG AND RAT SPINAL NEURONES
1 A series of compounds structurally related to glutamic acid has been tested on frog and rat spinal neurones. The substances… 
Highly Cited
1976
Highly Cited
1976
Separation of catecholamines and their metabolites by adsorption, ion-pair and soap chromatography.
Highly Cited
1974
Highly Cited
1974
Effects of drugs modifying catecholamine synthesis on plasma LH and ovulation in the rat.
Relatively large doses of alpha methyl paratyrosine (α-MPT) (400 mg/kg, i.p.) to inhibit catecholamine synthesis were capable of… 
Highly Cited
1973
Highly Cited
1973
Morphine-induced muscular rigidity in rats.
Highly Cited
1972
Highly Cited
1972
Effect of apomorphine on motility in rats.
Highly Cited
1970
Highly Cited
1970
L-Dihydroxyphenylalanine: Effect on S-Adenosylmethionine in Brain
Forty-five minutes after intraperitoneal injection of a single dose (100 milligrams per kilogram) of L-dihydroxyphenylalanine… 
Highly Cited
1969
Highly Cited
1969
L-Tyrosine-3, 5-3H Assay for Tyrosinase Development in Skin of Newborn Hamsters
Tyrosinase in hamster skin, measured by the production of 3HOH from L-tyrosine-3,5-3H, increases about sevenfold in specific… 
Highly Cited
1967
Highly Cited
1967
Properties of a new system of amine-storing cells in the gastric mucosa of the rat.
Highly Cited
1950
Highly Cited
1950
THE LOCALIZATION OF ENZYMES IN CELLS
1. Enzymes and related substances may be localized in cells either, (a) by separation and analysis of cell parts, or (b) by… 
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