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Levodopa
Known as:
beta-(3,4-Dihydroxyphenyl)-L-alanine
, 3,4-Dihydroxy-L-phenylalanine
, .beta.-(3,4-Dihydroxyphenyl)-L-alanine
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An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and…
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National Institutes of Health
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Related topics
Related topics
37 relations
Narrower (18)
2,4,5-trihydroxyphenylalanine quinone
2,4-dihydroxyphenylalanine
3,4,6-trihydroxyphenylalanine quinone
3-O-methyl-6-fluoro-dopa
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Broader (2)
Antiparkinson Agents
Dopa
Carbidopa / Levodopa
Carbidopa 10 MG / Levodopa 100 MG Disintegrating Oral Tablet
Carbidopa 10 MG / Levodopa 100 MG Oral Tablet
Carbidopa 10 MG / Levodopa 100 MG Oral Tablet [Sinemet]
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1981
Highly Cited
1981
Synthesis and antitumor activity of cysteinyl-3,4-dihydroxyphenylalanines and related compounds.
S. Ito
,
S. Inoue
,
Y. Yamamoto
,
K. Fujita
Journal of Medicinal Chemistry
1981
Corpus ID: 23611433
The natural catecholic amino acid 5-S-cysteinyl-3,4-dihydroxyphenylalanine (1) was selectively toxic to a variety of human tumor…
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Highly Cited
1980
Highly Cited
1980
Dopaminergic modulation of aldosterone secretion is independent of alterations in renin secretion.
J. Sowers
,
M. Tuck
,
M. Golub
,
E. Sollars
Endocrinology
1980
Corpus ID: 35670344
This study was designed to determine if dopaminergic modulation of aldosterone secretion is mediated through the renin…
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Highly Cited
1976
Highly Cited
1976
Progesterone biosynthesis and metabolism by ovarian follicles and isolated oocytes Xenopus laevis.
C. Thibier-Fouchet
,
O. Mulner
,
R. Ozon
Biology of Reproduction
1976
Corpus ID: 32961013
Ovarian follicles of Xen opus laevis exposed to exogenous radioactive pregnenolone have been observed to synthesize radioactive…
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Review
1975
Review
1975
Prolactin and breast carcinoma.
F. Smithline
,
L. Sherman
,
D. Kolodny
New England Journal of Medicine
1975
Corpus ID: 23563735
The recent findings regarding the possible relation of prolactin to human breast cancer are reviewed. Prolactin is a single…
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Highly Cited
1972
Highly Cited
1972
The metabolism of vitamin D 3 in the chick.
M. Haussler
,
H. Rasmussen
Journal of Biological Chemistry
1972
Corpus ID: 9233087
Abstract Physiological doses of radioactive vitamin D3 are administered to vitamin D-deficient chicks 16 hours prior to the…
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Highly Cited
1972
Highly Cited
1972
L-DOPA suppression of thyrotropin-releasing hormone response in man.
Stephen W . Spaulding
,
G. Burrow
,
R. Donabedian
,
M. V. Van Woert
Journal of Clinical Endocrinology and Metabolism
1972
Corpus ID: 44828102
ABSTRACT 500 μg of thyrotropin releasing hormone (TRH) was injected intravenously into eight Parkinsonian patients being treated…
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Highly Cited
1972
Highly Cited
1972
Inhibition of prolactin secretion and successful therapy of the Forbes-Albright syndrome with L-dopa.
R. W. Turkington
,
E. Gordon
Journal of Laboratory and Clinical Medicine
1972
Corpus ID: 32383781
Fourteen patients with galactorrhea, elevated serum prolactin levels (10–1130 ng/ml), and decreased urinary excretion of…
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Highly Cited
1960
Highly Cited
1960
Are dihydroxphenylalanine decarboxylase and 5-hydroxytrptophan decarboxylase individual enzymes?
E. Rosengren
Acta Physiologica Scandinavica
1960
Corpus ID: 30273106
Using an enzyme preparation from rabbit kidney cortex, the amino acids 3,4-dihydroxyphenylalanine and 5-hydroxytryptophan were…
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Highly Cited
1960
Highly Cited
1960
Serotonin Synthesis in Carcinoid Patients
A. Sjoerdsma
,
J. Oates
,
P. Zaltzman
,
S. Udenfriend
1960
Corpus ID: 76578943
RECENT investigations in our laboratories have shown that α-methyl-3,4-dihydroxy-DL-phenylalanine (α-methyl-dopa) is an effective…
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Highly Cited
1935
Highly Cited
1935
AN IMPROVED (PARAFFIN SECTION) METHOD FOR THE DOPA REACTION: WITH CONSIDERATIONS OF THE DOPA-POSITIVE CELL, AS STUDIED BY THIS METHOD
S. Becker
,
L. L. Praver
,
Harold W. Thatcher
1935
Corpus ID: 71220568
Progress in dermatologic histopathology has been meager during the past one or two decades. There have been a few reports of…
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