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lergotrile mesylate

Known as: Ergoline-8-acetonitrile, 2-chloro-6-methyl-, (8beta)-, monomethanesulfonate 
National Institutes of Health

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2 relations

Broader (1)

Ergolines
lergotrile

Papers overview

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Highly Cited
1980
Highly Cited
1980
Transsphenoidal microsurgery in the treatment of acromegaly and gigantism.
Twenty-five patients with acromegaly and 3 patients with gigantism underwent transsphenoidal microsurgery in an attempt to remove… 
1979
1979
Reduction in blood pressure in normal and spontaneously hypertensive rats by lergotrile mesylate
The acute administration of lergotrile mesylate to normal or spontaneously‐hypertensive rats (SHR) causes a prompt reduction in… 
1978
1978
Effect of the dopamine agonist, lergotrile mesylate, on circulating anterior pituitary hormones in man.
The effects of the ergoline derivative, lergotrile mesylate, on the serum levels of PRL, GH, TSH, LH, FSH, cortisol, and blood… 
1977
1977
Treatment of Parkinson's disease with lergotrile mesylate.
Lergotrile mesylate, an ergot alkaloid derivative and putative dopamine agonist, was effective in the majority of patients with… 
Highly Cited
1977
Highly Cited
1977
Predominant role of prolactin in stimulating the growth of 7, 12-dimethylbenz(a)anthracene-induced rat mammary tumor.
The effect of prolactin in supporting the growth of 7, 12-dimethylbenz(a)anthracene-induced mammary tumor in adult female Sprague… 
Highly Cited
1976
Highly Cited
1976
Studies on the role of the preoptic area in the control of reproductive function in the rat.
The present study was designed to determine the effects of bilateral lesions restricted to the medial preoptic area on… 
1976
1976
A Comparison of the Effects of CB-154 and Lergotrile Mesylate on Prolactin and Growth Hormone Secretion in Mice*
The influence of 2-bromo-alpha-ergocryptine (CB-154) and 2-chloro-6-methyl-ergoline-8beta-acetonitrile methanesulfonate… 
1976
1976
Prolactin binding to mammary gland, 7,12-dimethylbenz(a)-anthracene-induced mammary tumors, and liver in rats.
Specific binding of radioactively labeled prolactin was determined in membrane preparations from mammary glands and livers of… 
Highly Cited
1975
Highly Cited
1975
Inhibition of prolactin secretion by lergotrile mesylate: mechanism of action.
Lergotrile mesylate (2-chloro-6-methylergoline-8beta-acetonitrile, methane-sulphate salt) was shown to be a potent inhibitor of… 
Highly Cited
1975
Highly Cited
1975
Studies on the antiparkinsonian efficacy of lergotrile
The antiparkinsonian activity of lergotrile mesylate, a presumed dopaminergic receptor stimulating agent, was investigated in… 
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