laurocapram

Known as: 1-dodecylazacycloheptan-2-one, 1-dodecylhexahydro-2H-azepin-2-one 
A percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2016
0519822016

Papers overview

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2007
2007
The changes induced by biologically active substances in the permeability to K+ and calcein of liposomes composed of egg… (More)
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2001
2001
Purpose. This work aims to demonstrate a novel chemical assay for rapid screening and analysis of the mode of action of membrane… (More)
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1995
1995
Six model drugs were selected for this study based on their degree of lipophilicity as represented by their log P values (range… (More)
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1992
1992
In order to clarify the mechanism of action of laurocapram (Azone) on the skin permeation of drugs, the following experiments… (More)
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1992
1992
The in vitro treatment of shed snake skin and hairless rat skin with laurocapram resulted in dramatic decreases in the amounts of… (More)
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1992
1992
The promoting effect of cyclic monoterpenes, 1% limonene (CAS 5989-27-5) and 1% cineole (CAS 470-82-6), on percutaneous… (More)
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1988
1988
The study reports on penetration enhancers used to improve drug absorption through the skin. All experiments were carried out in… (More)
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1988
1988
The effect of 1-dodecylhexahydro-2H-azepine-2-one (Azone; laurocapran; 1) on the permeation of verapamil hydrochloride (2… (More)
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1984
1984
(E)-5-(2-Bromovinyl)-2'-deoxyuridine (bromovinyldeoxyuridine) was found to suppress the development of herpetic skin lesions and… (More)
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1982
1982
1-Dodecylazacycloheptan-2-one (Azone) is a new agent that enhances the percutaneous absorption of a number of different chemicals… (More)
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