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laurocapram

Known as: 1-dodecylazacycloheptan-2-one, 1-dodecylhexahydro-2H-azepin-2-one 
A percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Azepines

Narrower (1)

Azone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Role of veterinarians in providing residue-free animal food.
Veterinarians are not primarily concerned with the increase in production by treating the sick animals and poultry but their… 
1996
1996
Phase transitions of rat stratum corneum lipids by an electron paramagnetic resonance study and relationship of phase states to drug penetration.
1994
1994
Percutaneous absorption of azone following single and multiple doses to human volunteers.
Azone (1-dodecylazacycloheptan-2-one) is an agent that has been shown to enhance percutaneous absorption of drugs. Azone is… 
1993
1993
Keratinized epithelial transport of beta-blocking agents. III. Evaluation of enhancing effect on percutaneous absorption using model lipid liposomes.
We investigated the usefulness of a liposome composed of lipid components of stratum corneum as a system to evaluate the… 
1990
1990
Percutaneous absorption, metabolic profiling, and excretion of the penetration enhancer azone after multiple dosing of an azone-containing triamcinolone acetonide cream in humans.
Radioactive Azone (1.6%; 1-dodecylazacycloheptan-2-one) was incorporated in a therapeutic formulation containing triamcinolone… 
1989
1989
Enhancement of hydrocortisone permeation of human and hairless mouse skin by 1-dodecylazacycloheptan-2-one.
The influence of 1-dodecylazacycloheptan-2-one (Azone) on the in vitro permeation of hairless mouse skin and human epidermis by… 
Highly Cited
1988
Highly Cited
1988
Structure-activity relationship of 1-alkyl- or 1-alkenylazacycloalkanone derivatives as percutaneous penetration enhancers.
Nine azacycloalkanone (5-, 6-, or 7-member ring) derivatives with an alkyl or alkenyl (terpene) chain (10, 15, or 20 carbons… 
1988
1988
Influence of 1-dodecylhexahydro-2H-azepin-2-one (Azone) on the in vitro permeation of verapamil hydrochloride across rat, hairless mouse, and human cadaver skin.
The effect of 1-dodecylhexahydro-2H-azepine-2-one (Azone; laurocapran; 1) on the permeation of verapamil hydrochloride (2… 
1987
1987
Enhanced penetration of mitomycin C through hairless mouse and rat skin by enhancers with terpene moieties
The effects of four new percutaneous absorption enhancers containing an azacyclo ring and terpene chain (l‐geranylazacycloheptan… 
1987
1987
Inhibitory effect of Azone (1-dodecylazacycloheptan-2-one) on herpes simplex viruses. In vivo and in vitro studies.
Enhanced activity of antiviral agents, when mixed with a penetration enhancer like Azone (1-dodecylazacycloheptan-2-one) in… 
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