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laurocapram

Known as: 1-dodecylazacycloheptan-2-one, 1-dodecylhexahydro-2H-azepin-2-one 
A percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Azepines

Narrower (1)

Azone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Role of veterinarians in providing residue-free animal food.
Veterinarians are not primarily concerned with the increase in production by treating the sick animals and poultry but their… 
2000
2000
Transdermal iontophoretic delivery of timolol maleate in albino rabbits.
1996
1996
Phase transitions of rat stratum corneum lipids by an electron paramagnetic resonance study and relationship of phase states to drug penetration.
1993
1993
Keratinized epithelial transport of beta-blocking agents. III. Evaluation of enhancing effect on percutaneous absorption using model lipid liposomes.
We investigated the usefulness of a liposome composed of lipid components of stratum corneum as a system to evaluate the… 
Highly Cited
1990
Highly Cited
1990
Evaluation of In‐vitro Percutaneous Absorption across Human Skin and in Animal Models
Abstract— The in‐vitro permeability characteristics of human skin have been examined and compared with results in laboratory… 
1990
1990
Percutaneous absorption, metabolic profiling, and excretion of the penetration enhancer azone after multiple dosing of an azone-containing triamcinolone acetonide cream in humans.
Radioactive Azone (1.6%; 1-dodecylazacycloheptan-2-one) was incorporated in a therapeutic formulation containing triamcinolone… 
Highly Cited
1988
Highly Cited
1988
Structure-activity relationship of 1-alkyl- or 1-alkenylazacycloalkanone derivatives as percutaneous penetration enhancers.
Nine azacycloalkanone (5-, 6-, or 7-member ring) derivatives with an alkyl or alkenyl (terpene) chain (10, 15, or 20 carbons… 
1988
1988
Percutaneous absorption of hydroquinone in humans: effect of 1-dodecylazacycloheptan-2-one (azone) and the 2-ethylhexyl ester of 4-(dimethylamino)benzoic acid (Escalol 507).
Hydroquinone was found to penetrate readily human forehead skin in vivo following a single topical exposure, in an alcoholic… 
1987
1987
Enhanced penetration of mitomycin C through hairless mouse and rat skin by enhancers with terpene moieties
The effects of four new percutaneous absorption enhancers containing an azacyclo ring and terpene chain (l‐geranylazacycloheptan… 
Highly Cited
1984
Highly Cited
1984
Concentration-dependent enhancement of 1-dodecylazacycloheptan-2-one on the percutaneous penetration kinetics of triamcinolone acetonide.
The enhancing effect of 1-dodecylazacycloheptan-2-one (I) on the penetration kinetics of triamcinolone acetonide (II) and the… 
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