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lappaconitine

Known as: lappacontine 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

AconitineAnalgesics, Non-NarcoticAnti-Arrhythmia AgentsPsychotropic Drugs
analogs & derivatives

Papers overview

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2011
2011
Lappaconitine-loaded microspheres for parenteral sustained release: effects of formulation variables and in vitro characterization.
Lappaconitine instead of its hydrobromide salts has been encapsulated in poly (lactide-co-glycolide) acid (PLGA) microspheres by… 
Highly Cited
1997
Highly Cited
1997
Diterpenoid alkaloids as a new class of antiarrhythmic agents. Structure-activity relationship
The cardiotropic activities of 111 diterpene alkaloids and their synthetic derivatives having lycoctine, heteratisine, napelline… 
Review
1996
Review
1996
Recent studies on traditional Chinese medicinal plants
This review will discuss several new drugs which were discovered and developed in recent years from traditional Chinese medicines… 
1995
1995
Effect of diterpenoid alkaloids on cardiac sympathetic efferent and vagal afferent nerve activity.
1991
1991
Pharmacological studies on lappaconitine: antinociception and inhibition of the spinal action of substance P and somatostatin.
The pain response of mice to an injection of 0.5% formalin into the dorsal surface of a hindpaw is biphasic, with a first phase… 
1991
1991
Pharmacological studies of lappaconitine: supraspinal-spinal interaction in antinociception.
Changes in lappaconitine levels in blood, brain and spinal cord following subcutaneous (s.c.) injection were correlated with the… 
1990
1990
Roles of periaqueductal gray and nucleus raphe magnus on analgesia induced by lappaconitine, N-deacetyllappaconitine and morphine.
In the rat tail flick test, ip LA 6 mg/kg, icv DLA 60 micrograms and icv or with morphine 5 micrograms exhibited significant… 
1990
1990
Pharmacological studies of lappaconitine. Analgesia produced by intracerebroventricular, intracisternal and intrathecal injections.
The antinociceptive effects of lappaconitine (LA) and morphine (MOR) when injected intracerebroventricularly (i.c.v… 
1983
1983
Alkaloids of Aconitum barbatum
Aconitum barbatum var. puberulum 1 2 3 4 5 6 7 8 9 
1970
1970
Structure of lappaconitine
ConclusionsA structure has been proposed for lappaconitine on the basis of its chemical and spectral characteristics. 
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