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lanosterol synthase activity

Known as: (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming), 2,3-epoxysqualene lanosterol cyclase activity, oxidosqualene:lanosterol cyclase activity 
Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus. [EC:5.4.99.7, RHEA:14624… 
National Institutes of Health

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LSS geneLanosterol synthase

Papers overview

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2017
2017
Coumarin antifungal lead compounds, predicted mechanism of action
Introduction: Candida albicans is one of the most common causative fungi infection despite major efforts to control it. C… 
2016
2016
BB. Regulação de lanosterol sintase endógena para produção heteróloga de triterpenos
Introducao: Triterpenos sao moleculas formadas pela ciclizacao enzimatica da molecula de 2,3- oxidosqualeno e apresentam… 
2014
2014
Caracterización y Trazabilidad del Aceite de Sacha Inchi (Plukenetia volubilis Linneo).
El Sacha inchi (Plukenetia volubilis L.) en el Peru, forma parte de las especies silvestres usufructuadas del patrimonio natural… 
2005
2005
Molecular cloning , characterization , and functional expression of rat oxidosqualene cyclase cDNA ( cholesterol biosynthesis / cDNA cloning / active site / QW motif ) IKURO ABE AND
A cDNA encoding rat oxidosqualene lanosterol-cyclase [lanosterol synthase; (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol… 
2000
2000
Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase
The inhibition of squalene-hopene cyclase (SHC) (E.C. 5.4.99.-), an enzyme of bacterial membranes catalyzing the formation of… 
1993
1993
Baker's Yeast로부터 Oxidosqualene-Lanosterol Cyclase의 분리 및 성질에 관한 연구(II)
1987
1987
Posthatching evolution of in vivo mevalonate metabolism in chick liver.
The in vivo mevalonate incorporation into total nonsaponifiable lipids by chick liver was minimal after hatching and drastically… 
1984
1984
Influence of oxygenated sterol compounds on phase transitions in model membranes. A study by differential scanning calorimetry.
A marked influence of oxygenated sterol compounds (OSC: 7 alpha-, 7 beta-, and 25-hydroxycholesterol and 7-ketocholestanol) on… 
1980
1980
A deficiency of mixed function oxidase activities in the cholesterol biosynthetic pathway of human granulocytes.
Highly purified human granulocytes synthesize [14C]farnesol and [14C]squalene but not [14C]sterols from [14C]mevalonic acid… 
1979
1979
Fitoquimica de thymeleaceas: triterpenos y esteroles en hojas de thymelea hirsuta l
El estudio de la fraccion lipidica de las hojas de thymelea hirsuta l. (thymeleaceas) ha conducido a la identificacion de fitol y…