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Anti-obesity effect of Nelumbo nucifera leaves extract in mice and rats.
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Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and Aβ Pathology in a Transgenic Mouse Model of Alzheimer's Disease
TLDR
The administration of nobiletin decreased the Aβ burden and plaques in the hippocampus of APP-SL 7-5 Tg mice, suggesting that this natural compound has potential to become a novel drug for fundamental treatment of AD.
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Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant.
TLDR
Results suggest that the 40% ethanol extract of mangosteen has potent inhibitory activities of both histamine release and prostaglandin E2 synthesis, which is used as a Thai indigenous medicine and as an anti-allergy crude drug in Japan.
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Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells.
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Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation
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Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's β‐amyloid proteins
TLDR
The results suggest that Uncaria rhynchophylla has remarkably inhibitory effects on the regulation of Aβ fibrils, and it is concluded that this medicinal herb could have the potency to be a novel therapeutic agent to prevent and/or cure AD.
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Pharmacological properties of alpha-mangostin, a novel histamine H1 receptor antagonist.
In the isolated rabbit thoracic aorta and guinea-pig trachea, alpha-mangostin inhibited histamine-induced contractions in a concentration-dependent manner in the presence or absence of cimetidine, a…
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Nobiletin and its related flavonoids with CRE-dependent transcription-stimulating and neuritegenic activities.
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Pharmacological properties of α-mangostin, a novel histamine H1 receptor antagonist
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Isolation and structure of aaptamine a novel heteroaromatic substance possessing α-blocking activity from the sea sponge Aaptos aaptos
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